Evidence map›Paper›PMID 37724291›Full record

ArticleFrontiers in cellular and infection microbiology2023

Detailed characterisation of invasive aspergillosis in a murine model of X-linked chronic granulomatous disease shows new insights in infections caused by

Jill King, Ivy M Dambuza, Delyth M Reid, Raif Yuecel, Gordon D Brown, Adilia Warris

Abstract read
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In one paragraph

Article in Frontiers in cellular and infection microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jill KingMedical Research Council (MRC) Centre for Medical Mycology, University of Exeter, Exeter, United Kingdom.
Ivy M DambuzaMedical Research Council (MRC) Centre for Medical Mycology, University of Exeter, Exeter, United Kingdom.
Delyth M ReidMRC Centre for Medical Mycology Aberdeen Fungal Group, Institute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom.
Raif YuecelExeter Centre for Cytometrics, University of Exeter, Exeter, United Kingdom.
Gordon D BrownMedical Research Council (MRC) Centre for Medical Mycology, University of Exeter, Exeter, United Kingdom.
Adilia WarrisMedical Research Council (MRC) Centre for Medical Mycology, University of Exeter, Exeter, United Kingdom.

Funding

Department of HealthMedical Research Council MR/N006364/2Medical Research Council MR/V033417/1Wellcome Trust 086558Wellcome Trust 097377Wellcome Trust 217163
6 · The paper itself

Abstract

Introduction: Invasive aspergillosis (IA) is the most prevalent infectious complication in patients with chronic granulomatous disease (CGD). Yet, understanding of fungal pathogenesis in the CGD host remains limited, particularly with regards to Methods: We have used a murine model of X-linked CGD to investigate how the pathogenesis of IA varies between Results: We observed a lack of association between pulmonary pathology and infection outcome in gp91 Conclusion: We have provided an in-depth characterisation of the immune response to pulmonary aspergillosis in an X-linked CGD murine model. This provides the first description of distinct pulmonary inflammatory environments in

Indexed as

AspergillosisAspergillus nidulansGranulomatous Disease, ChronicInvasive Fungal InfectionsAnimalsAspergillus fumigatusCytokinesDisease Models, AnimalMiceMice, Inbred C57BLCytokinesAspergillus fumigatusAspergillus nidulanschronic granulomatous diseaseinfectioninflammationmurine

Identifiers

PMID37724291
PMCPMC10505440

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.