Evidence map›Paper›PMID 37724130›Full record

ArticleNeural computing & applications2023

Region-based evidential deep learning to quantify uncertainty and improve robustness of brain tumor segmentation.

Hao Li, Yang Nan, Javier Del Ser, Guang Yang

Abstract read
In one paragraph

Article in Neural computing & applications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. BPEN: Brain Posterior Evidential Network for trustworthy brain imaging analysis.Neural networks : the official journal of the International Neural Network Society · 2025
    Article
  9. DDEvENet: Evidence-based ensemble learning for uncertainty-aware brain parcellation using diffusion MRI.Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society · 2025
    Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hao LiNational Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, UK.
Yang NanNational Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, UK.
Javier Del SerTECNALIA, Basque Research and Technology Alliance (BRTA), Derio, Spain.
Guang YangNational Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, UK.ORCID 0000-0001-7344-7733

Funding

Medical Research Council MC_PC_21013Medical Research Council MR/V023799/1
6 · The paper itself

Abstract

Despite recent advances in the accuracy of brain tumor segmentation, the results still suffer from low reliability and robustness. Uncertainty estimation is an efficient solution to this problem, as it provides a measure of confidence in the segmentation results. The current uncertainty estimation methods based on quantile regression, Bayesian neural network, ensemble, and Monte Carlo dropout are limited by their high computational cost and inconsistency. In order to overcome these challenges, Evidential Deep Learning (EDL) was developed in recent work but primarily for natural image classification and showed inferior segmentation results. In this paper, we proposed a region-based EDL segmentation framework that can generate reliable uncertainty maps and accurate segmentation results, which is robust to noise and image corruption. We used the Theory of Evidence to interpret the output of a neural network as evidence values gathered from input features. Following Subjective Logic, evidence was parameterized as a Dirichlet distribution, and predicted probabilities were treated as subjective opinions. To evaluate the performance of our model on segmentation and uncertainty estimation, we conducted quantitative and qualitative experiments on the BraTS 2020 dataset. The results demonstrated the top performance of the proposed method in quantifying segmentation uncertainty and robustly segmenting tumors. Furthermore, our proposed new framework maintained the advantages of low computational cost and easy implementation and showed the potential for clinical application.

Indexed as

Brain tumor segmentationEvidential deep learningRobustnessUncertainty quantification

Identifiers

PMID37724130
PMCPMC10505106

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.