Evidence map›Paper›PMID 37724101›Full record

ReviewFrontiers in immunology2023

Regulation of lung inflammation by adiponectin.

Joo-Yeon Lim, Steven P Templeton

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
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  9. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Joo-Yeon LimDepartment of Microbiology and Immunology, Indiana University School of Medicine-Terre Haute, Terre Haute, IN, United States.
Steven P TempletonDepartment of Microbiology and Immunology, Indiana University School of Medicine-Terre Haute, Terre Haute, IN, United States.

Funding

Regulation of Inflammatory Pathology in Invasive AspergillosisR21AI163574 · NIAID · INDIANA UNIVERSITY INDIANAPOLIS · PI TEMPLETON, STEVEN P · 2021 to 2022
$347k
NIAID NIH HHS R21 AI163574
6 · The paper itself

Abstract

Adiponectin is an insulin sensitizing hormone that also plays a role in the regulation of inflammation. Although adiponectin can exert pro-inflammatory effects, more studies have reported anti-inflammatory effects, even in non-adipose tissues such as the lung. Obesity is considered an inflammatory disease, is a risk factor for lung diseases, and is associated with decreased levels of plasma adiponectin. The results of recent studies have suggested that adiponectin exerts anti-inflammatory activity in chronic obstructive pulmonary disease, asthma and invasive fungal infection. The signaling receptors of adiponectin, AdipoR1 and AdipoR2, are expressed by epithelial cells, endothelial cells, and immune cells in the lung. In this mini-review, we discuss the anti-inflammatory mechanisms of adiponectin in lung cells and tissues.

Indexed as

AsthmaPneumoniaAdiponectinEndothelial CellsHumansInflammationAdiponectinadiponectinadiponectin receptorsasthmaCOPDinfectious lung diseaseinflammatory pulmonary diseaselung immune responseobesity

Identifiers

PMID37724101
PMCPMC10505393

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.