Evidence map›Paper›PMID 37723484›Full record

ArticleBMC psychiatry2023

Dietary acid load, depression, and anxiety: results of a population-based study.

Hossein Bahari, Najmeh Seifi, Elahe Foroumandi, Fatemeh Kourepaz, Hediye Erfaniyan Shahabi, Kimia Ervin, Nahid Khabari, Gordon A Ferns, Majid Ghayour-Mobarhan

Abstract read
In one paragraph

Article in BMC psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hossein Bahari *Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran.
Najmeh Seifi *International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.
Elahe ForoumandiNon-Communicable Diseases Research Center, Department of Nutrition and Biochemistry, Faculty of Medicine, Sabzevar University of Medical Sciences, Sabzevar, Iran.
Fatemeh KourepazVarastegan Institute for Medical Sciences, Mashhad, Iran.
Hediye Erfaniyan ShahabiDepartment of Biology, Faculty of Sciences, Mashhad Branch of Islamic Azad University, Mashhad, Iran.
Kimia ErvinDepartment of Biology, Faculty of Sciences, Mashhad Branch of Islamic Azad University, Mashhad, Iran.
Nahid KhabariDepartment of Biology, Faculty of Sciences, Mashhad Branch of Islamic Azad University, Mashhad, Iran.
Gordon A FernsDivision of Medical Education, Brighton and Sussex Medical School, Falmer, Brighton, Sussex, UK.
Majid Ghayour-MobarhanInternational UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran. ghayourm@mums.ac.ir.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDietary acid load seems to be associated with psychological disorders through several mechanisms, and may barricade their treatment and recovery. The aim of current study was to evaluate the relationship between dietary acid load, using potential renal acid load (PRAL) and dietary acid load (DAL) scores, with the severity of depression and anxiety among Iranian adults.

methodsA total of 6531 participants aged 35-65 years were recruited in this cross-sectional study. A validated food frequency questionnaire (FFQ) was used to assess dietary intakes of participants. DAL was estimated using PRAL and DAL scores. Depression and anxiety were screened using Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI).

resultsIn the fully adjusted model, women with the highest DAL or PRAL had higher odds of more severe depression compared to those in the lowest category (OR = 1.20; 95% CI = 1.03-1.42 and OR = 1.20; 95% CI = 1.03-1.39, respectively). No significant association was observed between DAL and PRAL and depression severity in men and in the population as a whole. Regarding the association between PRAL and anxiety severity, there was no significant association when separated by sex. However, in the fully adjusted model for the whole population, participants in the highest tertile of PRAL had 13% greater odds of more severe anxiety than the lowest tertile (OR: 1.13, 95% CI: 1.01-1.13). No significant association was observed between DAL and anxiety severity in women, men or in the whole population.

conclusionWomen, but not men, with higher dietary acid load had significantly higher odds of having more severe depression. A significant positive association was also observed between dietary acid load and anxiety in the whole population.

Indexed as

AnxietyDepressionAdultAnxiety DisordersCross-Sectional StudiesFemaleHumansIranAnxietyDepressionDietary acid loadPotential renal acid load

Identifiers

PMID37723484
PMCPMC10506201

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.