Evidence map›Paper›PMID 37723354›Full record

ArticleCardiovascular and interventional radiology2023

Safety and Effectiveness of a Novel Tips Access Set with Steerable Cannula in a Swine Model.

PengXu Ding, Yujia Ma, Xiaoxia Zhu, Yijie Wu, John Ong, Pu Liu, Jiangqiang Xiao, Yuzheng Zhuge

Open access · hybridAbstract read
In one paragraph

Article in Cardiovascular and interventional radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Sharp recanalization of chronic total venous occlusions using the TipsStar Steerable Cannula.Journal of vascular surgery cases and innovative techniques · 2026
    Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

PengXu DingDepartment of Intervention, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yujia MaDepartment of Radiology, Shengjing Hospital, China Medical University, Shenyang, China.
Xiaoxia ZhuMedical Affairs, Becton, Dickinson and Company, Shanghai, China.
Yijie WuMedical Affairs, Becton, Dickinson and Company, Shanghai, China.
John OngResearch & Development, Becton, Dickinson and Company, Shanghai, China.
Pu LiuAnimal Lab, Shanghai Harborside Medical Technology Co.,Ltd, Shanghai, China.
Jiangqiang XiaoDepartment of Gastroenterology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, 321 Zhongshan Road, Gulou District, Nanjing, 210008, China. josedy@126.com.
Yuzheng ZhugeDepartment of Gastroenterology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, 321 Zhongshan Road, Gulou District, Nanjing, 210008, China. yuzheng9111963@aliyun.com.
Nanjing Drum Tower Hospital · CNChina Medical University · CNFirst Affiliated Hospital of Zhengzhou University · CNShanghai Harbour Engineering Design & Research Institute · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to assess the safety, effectiveness, and feasibility of the Liverty™ transjugular intrahepatic portosystemic shunt (TIPS) access set, which has an ergonomic handle that allows for in situ cannula tip deflection and a distal steerable cannula angle, versus the COOK® Rosch-Uchida Transjugular Liver Access Set (RUPS-100) in healthy pigs.

methodsTwelve pigs randomly underwent TIPS with the Liverty™ set or the RUPS-100 set. Three interventionalists performed 4 TIPS procedures, 2 with each set. The primary outcome was procedural success, defined as successful establishment of the intrahepatic portosystemic shunt and stent placement.

resultsThe shunt was successfully established in 11 pigs. The procedural success was achieved in all 6 pigs in the Liverty™ group and 5 out of 6 pigs for the RUPS-100 group (Fisher exact test, P > 0.999). The mean duration of puncture was shorter in the Liverty™ group versus the RUPS-100 group (12.3 ± 4.5 min vs. 16.2 ± 8.5 min), but without significant statistical difference (two sample t test, P = 0.359). The cannula angle was adjusted 69% of passes in the Liverty™ group, which was significantly higher than that in the RUPS-100 group (12%, P = 0.004). Overall, the TIPS procedural performance was comparable between the groups. Both sets were safe. No intraabdominal hemorrhage, vascular injuries, tissue or organ injuries, porto-biliary fistula, biliary peritonitis, and infection or abscess occurred in either group.

conclusionThe Liverty™ set is safe and has similar procedural metrics to the COOK® RUPS-100 set. It allows in situ adjustment of the angle of the stiffening cannula without increasing procedure time and lessens the occurrences of periprocedural complications.

Indexed as

Portasystemic Shunt, Transjugular IntrahepaticAnimalsCannulaLiverPortal VeinRetrospective StudiesSwineTreatment OutcomeEffectivenessPortal hypertensionSafetyTransjugular intrahepatic portosystemic shunt (TIPS)

Identifiers

PMID37723354
PMCPMC10547805
OpenAlexW4386825325

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.