Evidence map›Paper›PMID 37723273›Full record

ArticleInternational journal of obesity (2005)2023

Real-world costs of obesity-related complications over eight years: a US retrospective cohort study in 28,500 individuals.

Jonathan Pearson-Stuttard, Tania Banerji, Silvia Capucci, Elisabeth de Laguiche, Mads D Faurby, Christiane Lundegaard Haase, Kasper Sommer Matthiessen, Aimee M Near, Jenny Tse, Xiaohui Zhao and 1 more

Abstract read
In one paragraph

Article in International journal of obesity (2005), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jonathan Pearson-StuttardLane Clark & Peacock LLP, London, UK. Jonathan.Pearson-Stuttard@lcp.uk.com.ORCID 0000-0003-2175-9975
Tania BanerjiIQVIA, Durham, NC, USA.
Silvia CapucciNovo Nordisk A/S, Søborg, Denmark.
Elisabeth de LaguicheNovo Nordisk A/S, Søborg, Denmark.
Mads D FaurbyNovo Nordisk A/S, Søborg, Denmark.
Christiane Lundegaard HaaseNovo Nordisk A/S, Søborg, Denmark.ORCID 0000-0002-9992-3571
Kasper Sommer MatthiessenNovo Nordisk A/S, Søborg, Denmark.
Aimee M NearIQVIA, Durham, NC, USA.
Jenny TseIQVIA, Durham, NC, USA.
Xiaohui ZhaoIQVIA, Durham, NC, USA.
Marc EvansUniversity Hospital, Llandough, Penarth, Cardiff, UK.ORCID 0000-0003-0671-0778

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObesity-related complications (ORCs) are associated with high costs for healthcare systems. We assessed the relationship between comorbidity burden, represented by both number and type of 14 specific ORCs, and total healthcare costs over time in people with obesity in the USA.

methodsAdults (≥ 18 years old) identified from linked electronic medical records and administrative claims databases, with a body mass index measurement of 30-< 70 kg/m

resultsOf 28,583 included individuals, 12,686 had no ORCs, 7242 had one ORC, 4180 had two ORCs and 4475 had three or more ORCs in the baseline year. Annual adjusted direct healthcare costs increased with the number of ORCs and over the 8-year follow-up. Outpatient costs were the greatest contributor to baseline annual direct costs, irrespective of the number of ORCs. For specific ORCs, costs generally increased gradually over the follow-up; the largest percentage increases from year 1 to year 8 were observed for chronic kidney disease (+ 78.8%) and type 2 diabetes (+ 47.8%).

conclusionsIn a US real-world setting, the number of ORCs appears to be a cost driver in people with obesity, from the time of initial obesity classification and for at least the following 8 years.

Indexed as

Diabetes Mellitus, Type 2AdolescentAdultComorbidityHealth Care CostsHumansObesityRetrospective Studies

Identifiers

PMID37723273
PMCPMC10663144

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.