Trial reportInternational journal of obesity (2005)2023
A long-term follow-up of treatment for young children with obesity: a randomized controlled trial.
Trial report in International journal of obesity (2005), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01792531 (The More & Less Study), which is not on this map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The More & Less Study: A Randomized Controlled Trial Testing Different Treatment Approaches to Obesity in Preschoolers
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.
- Child and Adolescent Health Programs in Obesity and Depression: A Systematic Review and Meta-Analysis.Nutrients · 2025Pooled it
- Mindfulness-based interventions for improvement of lifestyle behaviors and body mass index in children with overweight or obesity: a systematic review and meta-analysis.European journal of pediatrics · 2025Pooled it
- Balancing digital and in-person support: parents' perspectives on delivering childhood obesity treatment.BMC public health · 2026Trial
- Parenting Training Plus Behavioral Treatment for Children With Obesity: A Randomized Clinical Trial.JAMA network open · 2025Trial
- Not for children's ears? Parents' insights into early childhood overweight and obesity treatment.Scandinavian journal of primary health care · 2026Article
- A coherent family support model (Co-Fam) for preventing and treating childhood overweight and obesity: protocol for a randomized hybrid type 2 effectiveness-implementation trial.BMC public health · 2026Article
- Metabolic Risk Factors Are Associated With Weight Status Change Over Four Years in Children Aged 4-6 Years With Obesity.Acta paediatrica (Oslo, Norway : 1992) · 2026Article
- Listening to children with obesity: lived experiences of hunger, cravings, and satiety.BMC pediatrics · 2026Article
- Municipality-Based Lifestyle Intervention of Childhood Overweight and Obesity: 4-Years Follow-Up on BMI Trajectories.Clinical obesity · 2026Article
- Two Sides of a Coin: Molecular, metabolic, and Phenotypic Convergence in Pediatric Undernutrition and Obesity.Current obesity reports · 2026Review
- Efficacy of an intervention in the nutritional status and consumption of ultra-processed foods in children with obesity treated in primary health care in Brazil.BMC nutrition · 2026Article
- No evidence for general or food-specific inhibitory control deficits in overweight university students: findings from flanker and Food Go/Nogo tasks.Frontiers in psychology · 2026Article
- Youth perspectives: experiences with a multidisciplinary weight management service, a qualitative study.BMC pediatrics · 2025Article
- Does deciding not to participate in a lifestyle intervention for children with obesity affect the long-term weight change?Obesity (Silver Spring, Md.) · 2025Observational
- Effectiveness of Smartphone App for the Treatment of Pediatric Obesity: A Randomized Controlled Trial.Children (Basel, Switzerland) · 2024Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEarly childhood obesity interventions supporting parents have the largest effects on child weight status. However, long-term follow-ups are lacking.
objectiveTo examine weight status 48 months after obesity treatment initiation for 4- to 6-year-olds.
methods177 families were recruited to the More and Less study, a 12-month randomized controlled trial (RCT) conducted in Sweden (2012-2017); 6 children were excluded due to medical diagnoses. Thus, 171 families (non-Swedish origin 59%, university degree 40%) were eligible for this 48-month follow-up with modified intention-to-treat (n = 114 had 48-month data, n = 34 dropped out, n = 23 lost to follow-up). The RCT compared 3 treatment approaches: a 10-week parent support program (1.5 h/w) with follow-up booster sessions (PGB) or without (PGNB), and standard outpatient treatment (ST). Treatment effects on primary outcome (BMI-SDS) and secondary outcomes (BMI, %IOTF25 i.e., the distance, in percent, above the cut-off for overweight) were assessed. Clinically significant reduction of BMI-SDS (≥0.5) was assessed with risk ratio. Sociodemographic factors and attendance were examined by three-way interactions.
resultsAfter 48 months (mean 50 months, range 38-67 months) mean (95% CI) BMI-SDS was reduced in all groups: PGB -0.45 (-0.18 to -0.73, p < 0.001), PGNB -0.34 (-0.13 to -0.55, p < 0.001), ST -0.25 (-0.10 to -0.40, p < 0.001), no significant difference between groups. A clinically significant reduction of BMI-SDS ≥ 0.5 was obtained in 53.7% of PGB which was twice as likely compared to ST, 33.0%, RR 2.03 (1.27 to 3.27, p = 0.003), with no difference to PGNB, 46.6% (p = 0.113). %IOTF25 was unchanged from baseline for PGB 4.50 (-1.64 to 10.63), and significantly lower compared to ST 11.92 (8.40 to 15.44) (p = 0.043). Sociodemographics or attendance had no effect.
conclusionThe intensive parent-support early childhood obesity intervention led to better weight status outcomes over time, though BMI-SDS alone did not reflect this. Further research should investigate how to assess weight changes in growing children. CLINICAL
trial registrationClinicaltrials.gov, NCT01792531 .
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.