Evidence map›Paper›PMID 37723006›Full record

ArticlePancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]2023

Bone health in children with recurrent and chronic pancreatitis: A multi-center cross sectional analysis.

Maisam Abu-El-Haija, Lindsey Hornung, Kate Ellery, Douglas S Fishman, Tanja Y Gonska, Cheryl Gariepy, Mark Lowe, Katie Larson Ode, Asim Maqbool, Maria Mascarenhas and 11 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Exocrine Pancreatic Insufficiency in Children - Challenges in Management.Pediatric health, medicine and therapeutics · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Maisam Abu-El-HaijaDivision of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA. Electronic address: maisam.haija@cchmc.org.
Lindsey HornungDivision of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Kate ElleryDivision of Pediatric Gastroenterology, Hepatology and Nutrition, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Douglas S FishmanDivision of Pediatric Gastroenterology, Hepatology, and Nutrition, Baylor College of Medicine and Texas Children's Hospital, Houston, TX, USA.
Tanja Y GonskaHospital for Sick Children, Toronto, ON, Canada.
Cheryl GariepyNationwide Children's Hospital, Columbus, OH, USA.
Mark LoweDepartment of Pediatrics, Washington University School of Medicine, Saint Louis, MO, USA.
Katie Larson OdeDepartment of Pediatrics, University of Iowa, Iowa City, IA, USA; Fraternal Order of Eagles Diabetes Research Center, University of Iowa, Iowa City, IA, USA.
Asim MaqboolDivision of Gastroenterology, Hepatology and Nutrition, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Maria MascarenhasDivision of Gastroenterology, Hepatology and Nutrition, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Veronique D MorinvilleMontreal Children's Hospital, McGill University, Montreal, QC, Canada.
Chee Y OoiDiscipline of Paediatrics and Child Health, School of Clinical Medicine, UNSW Medicine and Health, University of New South Wales and Department of Gastroenterology, Sydney Children's Hospital Randwick, Sydney, Australia.
Emily R PeritoUniversity of California San Francisco, San Francisco, CA, USA.
Sarah Jane SchwarzenbergUniversity of Minnesota Masonic Children's Hospital, Minneapolis, MN, USA.
Zachary M SellersDivision of Pediatric Gastroenterology, Hepatology and Nutrition, Stanford University, Palo Alto, CA, USA.
Babette S ZemelDivision of Gastroenterology, Hepatology and Nutrition, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Ying YuanDepartment of Biostatistics, University of Texas MD, Anderson Cancer Center, Huston, TX, USA.
Fuchenchu WangDepartment of Biostatistics, University of Texas MD, Anderson Cancer Center, Huston, TX, USA.
Aliye UcDepartment of Pediatrics, University of Iowa, Iowa City, IA, USA; Fraternal Order of Eagles Diabetes Research Center, University of Iowa, Iowa City, IA, USA; Radiation Oncology, University of Iowa, Iowa City, IA, USA.
Heidi J KalkwarfDivision of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer (CPDPC)

Funding

Consortium for the Study of Chronic Pancreatitis, Diabetes and Pancreatic Cancer: Coordinating and Data Management Center (CSCPDPC-CDMC)U01DK108328 · NIDDK · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Liang Li, Suyu Liu · 2015 to 2026
$32.8M
Vector Core-Core 2P30DK054759 · NIDDK · UNIVERSITY OF IOWA · PI Alejandro Antonio Pezzulo · 1998 to 2026
$30.5M
Year 9 Administrative Supplement to INSPPIRE 2U01DK108334 · NIDDK · UNIVERSITY OF IOWA · PI MARK E. LOWE, Aliye Uc · 2015 to 2026
$10.5M
University of Minnesota Clinical Center for the Study of Pancreatic DiseaseU01DK126300 · NIDDK · UNIVERSITY OF MINNESOTA · PI GREGORY J BEILMAN, Melena D. Bellin · 2020 to 2026
$3.9M
A Randomized Trial of a Web-based Non-Pharmacological Pain Intervention for Pediatric Chronic PancreatitisR01DK118752 · NIDDK · UNIVERSITY OF IOWA · PI PALERMO, TONYA M, UC, ALIYE · 2018 to 2022
$3.0M
Predicting Severity and Improving the Outcomes of Pediatric PancreatitisK23DK118190 · NIDDK · CINCINNATI CHILDRENS HOSP MED CTR · PI ABU-EL-HAIJA, MAISAM · 2018 to 2022
$947k
NIDDK NIH HHS K23 DK118190NIDDK NIH HHS P30 DK054759NIDDK NIH HHS R01 DK118752NIDDK NIH HHS U01 DK108328NIDDK NIH HHS U01 DK108334NIDDK NIH HHS U01 DK126300
6 · The paper itself

Abstract

BACKGROUND/

objectivesBone health of children with acute recurrent pancreatitis (ARP) and chronic pancreatitis (CP) is not well studied.

methodsThis retrospective study was performed at three sites and included data from INSPPIRE-2.

resultsOf the 87 children in the study: 46 had ARP (53%), 41 had CP (47%). Mean age was 13.6 ± 3.9 years at last DXA scan. The prevalence of low height-for-age (Z-score < -2) (13%, 10/78) and low bone mineral density (BMD) adjusted for height (Z-score < -2) (6.4%, 5/78) were higher than a healthy reference sample (2.5%, p < 0.0001 and p = 0.03, respectively).

conclusionChildren with ARP or CP have lower height and BMD than healthy peers. Attention to deficits in growth and bone mineral accrual in children with pancreatic disease is warranted.

Indexed as

Bone DensityPancreatitis, ChronicAdolescentChildCross-Sectional StudiesHumansRetrospective StudiesBone healthChildrenPancreatitis

Identifiers

PMID37723006
PMCPMC10843133

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.