ArticleAmerican journal of surgery2024
Contemporary trends in extent of surgery for differentiated thyroid cancer with extrathyroidal extension.
Article in American journal of surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 8 citations in OpenAlex.
- Preoperative and Intraoperative Assessment of Extrathyroidal Extension in Unilateral Papillary Thyroid Carcinoma: Does It Necessitate Total Thyroidectomy?Journal of surgical oncology · 2026Article
- A multimodal study on predicting extrathyroidal extension of papillary thyroid carcinoma based on radiopathomics.BMC endocrine disorders · 2026Article
- Patterns of Referral for Common Cancer Surgery in the United States.Annals of surgical oncology · 2025Article
- Coagulation and thyroiditis are factors associated with adverse pathological features in differentiated thyroid cancer: a retrospective cohort study.BMC surgery · 2025Article
- The overtreatment of papillary thyroid microcarcinoma in the community.American journal of surgery · 2024Article
- Comparing therapeutic outcomes: radioactive iodine therapy versus non-radioactive iodine therapy in differentiated thyroid cancer.Frontiers in endocrinology · 2024Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
objectiveAlthough lobectomy is acceptable for patients with small, low-risk differentiated thyroid cancer (DTC), gross extrathyroidal extension (ETE) remains an indication for total thyroidectomy (TT). Here we investigate evolving trends in extent of surgery for + ETE DTC.
methodsPatients with +ETE DTC who underwent resection from 2010 to 2020 were identified using the National Cancer Database. The primary outcome was performance of TT versus lobectomy.
resultsAmong 5851 patients, most were female (79.7%), white (80.0%), and had minimal ETE (91.8%). Ninety-two percent of patients received TT. Year of treatment was influential (p < 0.001), with increasing lobectomy rates in later years. On multivariable analyses, a decreased likelihood of TT was seen in years 2015 through 2020.
conclusionsMost patients with +ETE DTC underwent guideline-concordant TT, but lobectomy rates doubled over the study period. These findings may reflect increased preference for lobectomy in low-risk DTC, but could undertreat patients with high-risk features.
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