Evidence map›Paper›PMID 37722502›Full record

ReviewMolecular and cellular endocrinology2023

Pyrethroid pesticide exposure and placental effects.

Joshua Wolfe, Carmen Marsit

Open access · hybridAbstract readReview
In one paragraph

Review in Molecular and cellular endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
5.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Joshua WolfeGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Carmen MarsitGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, GA, USA. Electronic address: carmen.j.marsit@emory.edu.
Emory University · US

Funding

Pilot Project ProgramP30ES019776 · NIEHS · EMORY UNIVERSITY · PI William Michael Caudle · 2013 to 2026
$22.6M
Characterizing the functional genomic atlas of human placenta and unveiling the prenatal programming of early-life developmentR01HD108310 · NICHD · EMORY UNIVERSITY · PI Jia Chen, Carmen Joseph Marsit · 2023 to 2026
$2.8M
Placental Functional Networks Linking Developmental Pesticide Exposure and Offspring NeurodevelopmentR01ES029212 · NIEHS · EMORY UNIVERSITY · PI CAUDLE, WILLIAM MICHAEL, CHEN, JIA · 2018 to 2022
$2.7M
NICHD NIH HHS R01 HD108310NIEHS NIH HHS P30 ES019776NIEHS NIH HHS R01 ES029212
6 · The paper itself

Abstract

Human exposures to pyrethroid pesticides have increased in recent years following the bans and sanctions placed on other families of pesticides. Although pyrethroids are currently widely used across the United States and throughout the world, and their overt neurological toxicity classified, the extent of their toxicity through low dose and chronic exposures on humans is less well characterized, particularly when it comes to prenatal exposures, their impacts on neurodevelopment, and any role for the placenta in those effects. In this review, we assess the state of research on pyrethroid pesticide exposure and placental effects. These studies presented hormone disrupting, genotoxic, neurodevelopmental and neurobehavioral effects, among others, following prenatal pyrethroid exposures, and highlights a need for future research to assess gaps relating to effects in the human placenta and mechanisms of toxicity as well as shortcomings in the reproducibility and standardization of the methodologies presented.

Indexed as

PesticidesPlacentaPyrethrinsAnimalsFemaleHumansMaternal ExposurePregnancyPrenatal Exposure Delayed EffectsPesticidesPyrethrinsDeltamethrinHumanInsecticideMousePlacentaPyrethroid

Identifiers

PMID37722502
PMCPMC10591723
OpenAlexW4386800060

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.