Evidence map›Paper›PMID 37722488›Full record

ArticleAdvances in nutrition (Bethesda, Md.)2023

Perspective: A Research Roadmap about Ultra-Processed Foods and Human Health for the United States Food System: Proceedings from an Interdisciplinary, Multi-Stakeholder Workshop.

Lauren E O'Connor, Kelly A Higgins, Katarina Smiljanec, Robert Bergia, Andrew W Brown, David Baer, Cindy Davis, Mario G Ferruzzi, Kevin Miller, Sylvia Rowe and 20 more

Open access · hybridAbstract read
In one paragraph

Article in Advances in nutrition (Bethesda, Md.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
10.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
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  9. Dietary Advanced Glycation End Products and Cardiovascular-Kidney-Metabolic Complications.Clinical journal of the American Society of Nephrology : CJASN · 2026
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  12. Article
  13. Research roadmap for ultra-processed foods in the context of the Australian food system.Nutrition & dietetics : the journal of the Dietitians Association of Australia · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors at 15 institutions in 3 countries.

Lauren E O'ConnorAgricultural Research Service, US Department of Agriculture, Beltsville, MD, United States. Electronic address: lauren.oconnor@usda.gov.
Kelly A HigginsAgricultural Research Service, US Department of Agriculture, Beltsville, MD, United States.
Katarina SmiljanecArcher Daniels Midland (ADM), Erlanger, KY, United States.
Robert BergiaArcher Daniels Midland (ADM), Decatur, IL, United States.
Andrew W BrownUniversity of Arkansas for Medical Sciences and Arkansas Children's Research Institute, Little Rock, AR, United States.
David BaerAgricultural Research Service, US Department of Agriculture, Beltsville, MD, United States.
Cindy DavisAgricultural Research Service, US Department of Agriculture, Beltsville, MD, United States.
Mario G FerruzziDepartment of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR, United States; Arkansas Children's Nutrition Center, Little Rock, AR, United States.
Kevin MillerBell Institute of Health & Nutrition, General Mills, Minneapolis, MN, United States.
Sylvia RoweSR Strategy, Washington, DC, United States.
Janice M W RuedaArcher Daniels Midland (ADM), Decatur, IL, United States.
Aline AndresUniversity of Arkansas for Medical Sciences and Arkansas Children's Nutrition Center, Little Rock, AR, United States.
Sean B CashFriedman School of Nutrition Science and Policy at Tufts University, Boston, MA, United States.
John CouplandPenn State University, University Park, PA, United States.
Meghan CrimminsUniversity of Arkansas for Medical Sciences and Arkansas Children's Nutrition Center, Little Rock, AR, United States.
Chelsey FieckeDepartment of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR, United States; Arkansas Children's Nutrition Center, Little Rock, AR, United States.
Ciarán G FordeWageningen University and Research, Wageningen, The Netherlands.
Naomi K FukagawaAgricultural Research Service, US Department of Agriculture, Beltsville, MD, United States.
Kevin D HallNational Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, United States.
Bruce HamakerPurdue University, West Lafayette, IN, United States.
Kirsten A HerrickNational Cancer Institute, National Institutes of Health, Rockville, MD, United States.
Julie M HessAgricultural Research Service, US Department of Agriculture, Grand Forks, ND, United States.
Lise Aj HeuvenWageningen University and Research, Wageningen, The Netherlands.
Filippa JuulNew York University School of Global Public Health, New York, NY, United States.
Fiona C MalcomsonNewcastle University, Newcastle upon Tyne, United Kingdom.
Euridice Martinez-SteeleFaculdade de Saude Pública, Universidade de São Paulo, São Paulo, Brazil.
Richard D MattesPurdue University, West Lafayette, IN, United States.
Mark MessinaSoy Nutrition Institute Global, Pittsfield, MA, United States.
Alyson MitchellFood Science and Technology, University of California at Davis, CA, United States.
Fang Fang ZhangFriedman School of Nutrition Science and Policy at Tufts University, Boston, MA, United States.
University of Arkansas for Medical Sciences · USAgricultural Research Service · USArcher Daniels Midland (United States) · USPurdue University West Lafayette · USTufts University · USUnited States Department of Agriculture · USWageningen University & Research · NLArkansas Children's Nutrition Center · USErlanger Health System · USGeneral Mills (United States) · USNational Cancer Institute · USNational Institute of Diabetes and Digestive and Kidney Diseases · USNewcastle University · GBNew York University · USPennsylvania State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our objective was to convene interdisciplinary experts from government, academia, and industry to develop a Research Roadmap to identify research priorities about processed food intake and risk for obesity and cardiometabolic diseases (CMD) among United States populations. We convened attendees at various career stages with diverse viewpoints in the field. We held a "Food Processing Primer" to build foundational knowledge of how and why foods are processed, followed by presentations about how processed foods may affect energy intake, obesity, and CMD risk. Breakout groups discussed potential mechanistic and confounding explanations for associations between processed foods and obesity and CMD risk. Facilitators created research questions (RQs) based on key themes from discussions. Different breakout groups convened to discuss what is known and unknown for each RQ and to develop sub-RQs to address gaps. Workshop attendees focused on ultra-processed foods (UPFs; Nova Group 4) because the preponderance of evidence is based on this classification system. Yet, heterogeneity and subjectivity in UPF classification was a challenge for RQ development. The 6 RQs were: 1) What objective methods or measures could further categorize UPFs, considering food processing, formulation, and the interaction of the two? 2) How can exposure assessment of UPF intake be improved? 3) Does UPF intake influence risk for obesity or CMDs, independent of diet quality? 4) What, if any, attributes of UPFs influence ingestive behavior and contribute to excess energy intake? 5) What, if any, attributes of UPFs contribute to clinically meaningful metabolic responses? 6) What, if any, external environmental factors lead people to consume high amounts of UPFs? Uncertainty and complexity around UPF intake warrant further complementary and interdisciplinary causal, mechanistic, and methodological research related to obesity and CMD risk to understand the utility of applying classification by degree of processing to foods in the United States.

Indexed as

Fast FoodsFood, ProcessedDietEnergy IntakeFood HandlingHumansObesitybuilt environmentcardiometabolic healthdietary assessmentfood engineeringfood environmentfood sciencefood technologyingestive behaviorNova classification systemultra-processed food

Identifiers

PMID37722488
PMCPMC10721509
OpenAlexW4386799647

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.