Evidence map›Paper›PMID 37722206›Full record

ReviewThrombosis research2023

Breaking down tumor thrombus: Current strategies for medical management.

Harsha Tathireddy, Douglas Rice, Kylee Martens, Sudeep Shivakumar, Joseph Shatzel

Open access · greenAbstract readReview
In one paragraph

Review in Thrombosis research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Case - Caval thrombectomy for metastatic breast cancer.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Primary adrenal angiosarcoma: a rare case presentation.Journal of surgical case reports · 2025
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Inferior Vena Cava Tumor Thrombus in the Emergency Department: A Case Report.Clinical practice and cases in emergency medicine · 2025
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Harsha TathireddyDivision of Hematology and Medical Oncology, Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA. Electronic address: tathired@ohsu.edu.
Douglas RiceDepartment of Medicine, Oregon Health & Science University, Portland, OR, USA.
Kylee MartensDivision of Hematology and Medical Oncology, Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA.
Sudeep ShivakumarDepartment of Medicine, Dalhousie University, Halifax, Canada.
Joseph ShatzelDivision of Hematology and Medical Oncology, Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA; Department of Biomedical Engineering, Oregon Health & Science University, OR, USA.
Oregon Health & Science University · USDalhousie University · CA

Funding

Evaluating the Safety and Efficacy of Targeting the Contact Pathway to Prevent Device Associated Thrombosis.R01HL151367 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI SHATZEL, JOSEPH JAMES · 2020 to 2024
$1.5M
NHLBI NIH HHS R01 HL151367
6 · The paper itself

Abstract

Tumor thrombus, the intravascular extension of tumor into adjacent blood vessels, is frequently encountered in patients with renal cell carcinoma and hepatocellular carcinoma, and often involves the abdominal vasculature including the renal vein, portal vein, and the inferior vena cava. While a bland thrombus is composed of platelets and fibrin, in contrast, a tumor thrombus refers to an organized collection of tumor cells. Though oftentimes detected incidentally on imaging, tumor thrombus may have significant clinical implications and can be challenging to differentiate from bland thrombus. Additionally, the optimal management of tumor thrombus, including the use of anticoagulation, remains poorly described. This review summarizes common causes of tumor thrombus, as well as its impact on staging, prognosis, and treatment.

Indexed as

Carcinoma, Renal CellKidney NeoplasmsThrombosisHumansNephrectomyRetrospective StudiesVena Cava, InferiorAnticoagulationBland thrombusCancerPrognosisThrombosisTumor thrombusVenous tumor thrombus

Identifiers

PMID37722206
PMCPMC11027429
OpenAlexW4386629639

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.