Evidence map›Paper›PMID 37722048›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Tyler Cobb, Irene Hwang, Michael Soukar, Sim Namkoong, Uhn-Soo Cho, Maryam Safdar, Myungjin Kim, Robert J Wessells, Jun Hee Lee

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Molecular mechanism on autophagy associated cardiovascular dysfunction inFrontiers in cell and developmental biology · 2025
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Tyler CobbDepartment of Physiology, Wayne State University School of Medicine, Detroit, MI 48201.
Irene HwangDepartment of Molecular & Integrative Physiology, University of Michigan, Ann Arbor, MI 48109.
Michael SoukarDepartment of Molecular & Integrative Physiology, University of Michigan, Ann Arbor, MI 48109.ORCID 0000-0002-7238-1055
Sim NamkoongDepartment of Molecular & Integrative Physiology, University of Michigan, Ann Arbor, MI 48109.
Uhn-Soo ChoDepartment of Biological Chemistry, University of Michigan, Ann Arbor, MI 48109.
Maryam SafdarDepartment of Physiology, Wayne State University School of Medicine, Detroit, MI 48201.ORCID 0000-0002-1123-8976
Myungjin KimDepartment of Molecular & Integrative Physiology, University of Michigan, Ann Arbor, MI 48109.
Robert J WessellsDepartment of Physiology, Wayne State University School of Medicine, Detroit, MI 48201.ORCID 0000-0002-4516-3183
Jun Hee LeeDepartment of Molecular & Integrative Physiology, University of Michigan, Ann Arbor, MI 48109.ORCID 0000-0002-2200-6011
University of Michigan · USWayne State University · USKangwon National University · KR

Funding

Pilot and Feasibility (P and F) ProgramP30DK089503 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI RANDY J SEELEY · 2010 to 2026
$20.3M
Octpamine controls adaptation to endurance exercise in DrosophilaR01AG059683 · NIA · WAYNE STATE UNIVERSITY · PI Robert John Wessells · 2018 to 2026
$3.0M
The molecular mechanisms of nutrient- and stress-dependent mTORC1 regulation mediated by human Sestrin2.R01DK111465 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHO, UHN-SOO · 2016 to 2020
$2.4M
Sestrins-mediated integration of leucine and exercise benefits for mitochondrial homeostasisR01AG079163 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Myungjin Kim, Jun Hee Lee · 2023 to 2026
$2.1M
Detroit Cardiovascular Training ProgramT32HL120822 · NHLBI · WAYNE STATE UNIVERSITY · PI LEVY, PHILLIP DAVID · 2014 to 2023
$1.8M
Mechanisms underlying Hepatoprotective Roles of Sestrin2R01DK102850 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LEE, JUN HEE · 2015 to 2019
$1.7M
Seq-Scope: Microscopic Examination of Spatial Single Cell Transcriptome in Cell and Tissue SenescenceUG3CA268091 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LEE, JUN HEE · 2021 to 2022
$1.1M
Protein inclusions in non-alcoholic steatohepatitisR01DK114131 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LEE, JUN HEE · 2018 to 2020
$1.0M
Beneficial effects of Sestrin protein for muscle health during aging and exerciseK01AG061236 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KIM, MYUNGJIN · 2019 to 2023
$600k
Sestrin1-knockout mice as a model of facilitated muscle agingR21AG045432 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LEE, JUN HEE · 2013 to 2014
$428k
Octopamine Mediates Benefits Of Endurance Exercise In DrosophilaR21AG055712 · NIA · WAYNE STATE UNIVERSITY · PI WESSELLS, ROBERT JOHN · 2017 to 2018
$424k
NCI NIH HHS UG3 CA268091NHLBI NIH HHS T32 HL120822NIA NIH HHS K01 AG061236NIA NIH HHS R01 AG059683NIA NIH HHS R01 AG079163NIA NIH HHS R21 AG045432NIA NIH HHS R21 AG055712NIDDK NIH HHS P30 DK089503NIDDK NIH HHS R01 DK102850NIDDK NIH HHS R01 DK111465NIDDK NIH HHS R01 DK114131
6 · The paper itself

Abstract

Mammalian

Indexed as

Drosophila ProteinsFibronectinsAnimalsAnimals, Genetically ModifiedAutophagyDrosophilaHumansMammalsMiceTranscription FactorsDrosophila ProteinsFibronectinsFNDC5 protein, humanFNDC5 protein, mouseTranscription FactorsautophagycardiacexerciseFNDC5Irisin

Identifiers

PMID37722048
PMCPMC10523451
OpenAlexW4386824179

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.