Evidence map›Paper›PMID 37721913›Full record

ArticleBiomedica : revista del Instituto Nacional de Salud2023

Meningeal cryptococcosis and SARS-CoV-2 infection in people living with HIV/AIDS.

Fernando Antonio Messina, Andrés Benchetrit, Andrea Bocassi, María de Las Mercedes Romero, Sofía Bauer, Emmanuel Marín, Facundo Bertera, Guillermo Onis, Matías Enzenhofer, Milagro Sánchez and 3 more

Abstract read
In one paragraph

Article in Biomedica : revista del Instituto Nacional de Salud, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Fernando Antonio MessinaUnidad Micología, Hospital de Enfermedades Infecciosas Francisco Javier Muñiz, Buenos Aires, Argentina. fmessina35@gmail.com.
Andrés BenchetritSala 21, Hospital de Enfermedades Infecciosas F. J. Muñiz Hospital, Buenos Aires, Argentina. benche2000@hotmail.com.
Andrea BocassiLaboratorio Central Hospital de Infecciosas, Francisco Javier Muñiz Hospital, Buenos Aires, Argentina. andiboc@gmail.com.
María de Las Mercedes RomeroUnidad Micología, Hospital de Enfermedades Infecciosas Francisco Javier Muñiz, Buenos Aires, Argentina. mecharomero@gmail.com.
Sofía BauerDivisión SIDA, Hospital de infecciosas Francisco Javier Muñiz Hospital, Buenos Aires, Argentina. sofiabauers@gmail.com.
Emmanuel MarínUnidad Micología, Hospital de Enfermedades Infecciosas Francisco Javier Muñiz, Buenos Aires, Argentina. emamarin@hotmail.com.
Facundo BerteraDivisión Farmacia, Hospital de infecciosas Francisco Javier Muñiz Hospital, Buenos Aires, Argentina. fbertera@ffyb.uba.ar.
Guillermo OnisSala 20, Hospital de Infecciosas Francisco Javier Muñiz Hospital, Buenos Aires, Argentina. guillonis@gmail.com.
Matías EnzenhoferDivisión SIDA, Hospital de infecciosas Francisco Javier Muñiz Hospital, Buenos Aires, Argentina. matiasenzenhofer@gmail.com.
Milagro SánchezDivisión SIDA, Hospital de infecciosas Francisco Javier Muñiz Hospital, Buenos Aires, Argentina. milagritus13@hotmail.com.
Lilia MammanaUnidad Virología, Hospital de Infecciosas F. J. Muñiz Hospital, Buenos Aires, Argentina. lilymammana@hotmail.com.
Dana MijalovskyDivisión SIDA, Hospital de infecciosas Francisco Javier Muñiz Hospital, Buenos Aires, Argentina. danamijalovsky@gmail.com.
Gabriela SantisoUnidad Micología, Hospital de Enfermedades Infecciosas Francisco Javier Muñiz, Buenos Aires, Argentina. santisogabi@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionFungal infections in patients with COVID-19 was one of the most debated topics during the pandemic.

objectivesTo analyze the clinical characteristics and evolution of people living with HIV/AIDS and coinfection with cryptococcus and COVID-19 (group A) or without it (group B). MATERIALS AND

methodsThis is an analytical and retrospective study. We reviewed medical records of patients with meningeal cryptococcosis between April 2020 and May 2021.

resultsWe studied 65 people living with HIV/AIDS and with cryptococcosis infection diagnosed from April 2020 to May 2021. Fifteen patients with HIV/AIDS suffered from cryptococcosis and COVID-19, and out of these, 14 presented meningitis (group A), while 28 suffered from meningeal cryptococcosis, but did not have COVID-19 (group B).

conclusionsNo statistically significant differences were observed between the two groups (A and B) considering: intracranial hypertension, presence of Cryptococcus antigens in cerebrospinal fluid, sensorium deterioration or mortality. The detection of Cryptococcus antigens in serum by lateral flow assay was highly effective to rapidly diagnose cryptococcosis in patients with HIV/AIDS who also developed COVID-19. Patients of both groups consulted for cryptoccocosis sometime after, in comparison with the pre-pandemic cases related to this infection.

Indexed as

Acquired Immunodeficiency SyndromeCOVID-19CryptococcosisHumansRetrospective StudiesSARS-CoV-2coinfectionCOVID-19cryptococcalCryptococcusHIV infectionsmeningitisSARS-Cov-2

Identifiers

PMID37721913
PMCPMC10586798

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.