Evidence map›Paper›PMID 37721905›Full record

ArticleBiomedica : revista del Instituto Nacional de Salud2023

Pseudoepitheliomatous hyperplasia: Squamous cell carcinoma versus oral paracoccidioidomycosis, a case from a dermatological perspective

Lina M Osorio-Cock, Sandra Catalina Jaramillo-Pulgarín, Alba P Ferrín-Bastidas, Diana Y Molina-Colorado, Óscar M Gómez-Guzmán, Alejandra Zuluaga, Juan G McEwen-Ochoa, Martha E Urán-Jiménez, María Del Pilar Jiménez-Alzate

Open access · diamondAbstract readEnglish Abstract
In one paragraph

Article in Biomedica : revista del Instituto Nacional de Salud, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Lina M Osorio-CockGrupo Micología Médica, Departamento de Microbiología y Parasitología, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia; Escuela de Ciencias de la Salud, Universidad Pontificia Bolivariana, Medellín, Colombia.. lina.osorio.co@gmail.com.
Sandra Catalina Jaramillo-PulgarínMedicáncer, Medellín, Colombia; Departamento de Dermatología, Universidad de Antioquia, Medellín, Colombia.. caja05@gmail.com.
Alba P Ferrín-BastidasMedicáncer, Medellín, Colombia. apferrinb@gmail.com.
Diana Y Molina-ColoradoGrupo Micología Médica, Departamento de Microbiología y Parasitología, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia. diana.molina@udea.edu.co.
Óscar M Gómez-GuzmánGrupo de Biología Celular y Molecular, Corporación para Investigaciones Biológicas, Medellín, Colombia. oscargomez24@hotmail.com.
Alejandra ZuluagaGrupo de Micología Médica y Experimental, Corporación para Investigaciones Biológicas, Medellín, Colombia. azuluaga@cib.org.co.
Juan G McEwen-OchoaGrupo Micología Médica, Departamento de Microbiología y Parasitología, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia; Grupo de Biología Celular y Molecular, Corporación para Investigaciones Biológicas, Medellín, Colombia. juan.mcewen@udea.edu.co.
Martha E Urán-JiménezGrupo Micología Médica, Departamento de Microbiología y Parasitología, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia. martha.uran@udea.edu.co.
María Del Pilar Jiménez-AlzateGrupo Micología Médica, Departamento de Microbiología y Parasitología, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia. delpilar.jimenez@udea.edu.co.
Universidad de Antioquia · COCorporación para Investigaciones Biológicas · COMunicipality of Medellín · COUniversidad Pontificia Bolivariana · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Paracoccidioidomycosis is a systemic mycosis endemic in Latin America. The most frequent form involves a chronic compromise of the lungs, skin, and mucosa. The patient started with a single oral lesion that lasted for several years. The absence of other symptoms pointed out a possible malignant neoplasm, specifically a squamous cell carcinoma. Differentiation between both diagnoses –fungal infection and carcinoma– depends on the results of the direct examination, the histopathological study, and the initial and subsequent cultures. However, in this case, those findings were not conclusive. The coexistence of both diagnoses is frequent and increases the diagnostic challenge. After several consultations and tests, direct examination, immunodiffusion and real-time PCR findings the multifocal chronic paracoccidioidomycosis diagnosis was confirmed. This case warns about a systematical absence of clinical suspicion of endemic mycoses before the appereance of mucocutaneous lesions, which can be produced by fungi like Paracoccidioides spp, and the importance of considering those mycoses among the differential diagnoses.

Indexed as

Carcinoma, Squamous CellParacoccidioidomycosisCell DifferentiationHumansHyperplasiaSkincarcinomadiagnosisdifferentialmycosesParacoccidioidesparacoccidioidomycosisreal-time polymerase chain reactionsquamous cell

Identifiers

PMID37721905
PMCPMC10586879
OpenAlexW4386828982

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.