Trial reportNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics2023
Frequency-Dependent Reduction of Cybersickness in Virtual Reality by Transcranial Oscillatory Stimulation of the Vestibular Cortex.
Trial report in Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 23 citations in OpenAlex.
- Functional head impulse testing for detection and quantification of vestibular dysfunction in multiple sclerosis.Journal of neurology · 2026Article
- Article
- The Use of Metaverse in Radiology: A Systematic Review.Health science reports · 2025Review
- Virtual Reality-Based Rehabilitation Therapy.Physiological research · 2025Review
- Effectiveness of Virtual and Augmented Reality for Emergency Healthcare Training: A Randomized Controlled Trial.Healthcare (Basel, Switzerland) · 2025Article
- Reduction of cognitive fatigue and improved performance at a VR-based driving simulator using tRNS.iScience · 2024Article
- Virtual Reality in Acute and Chronic Pain Medicine: An Updated Review.Current pain and headache reports · 2024Review
- Being in Virtual Reality and Its Influence on Brain Health-An Overview of Benefits, Limitations and Prospects.Brain sciences · 2024Review
- A bibliometric analysis of transcranial alternating current stimulation.Frontiers in neuroscience · 2024Article
- A machine learning approach to evaluate the impact of virtual balance/cognitive training on fall risk in older women.Frontiers in computational neuroscience · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 3 institutions in 2 countries.
Funding
Abstract
Virtual reality (VR) applications are pervasive of everyday life, as in working, medical, and entertainment scenarios. There is yet no solution to cybersickness (CS), a disabling vestibular syndrome with nausea, dizziness, and general discomfort that most of VR users undergo, which results from an integration mismatch among visual, proprioceptive, and vestibular information. In a double-blind, controlled trial, we propose an innovative treatment for CS, consisting of online oscillatory imperceptible neuromodulation with transcranial alternating current stimulation (tACS) at 10 Hz, biophysically modelled to reach the vestibular cortex bilaterally. tACS significantly reduced CS nausea in 37 healthy subjects during a VR rollercoaster experience. The effect was frequency-dependent and placebo-insensitive. Subjective benefits were paralleled by galvanic skin response modulation in 25 subjects, addressing neurovegetative activity. Besides confirming the role of transcranially delivered oscillations in physiologically tuning the vestibular system function (and dysfunction), results open a new way to facilitate the use of VR in different scenarios and possibly to help treating also other vestibular dysfunctions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.