Evidence map›Paper›PMID 37721636›Full record

ArticleACS applied bio materials2023

Biosynthesis of Zinc Oxide Nanoparticles on l-Carnosine Biofunctionalized Polyacrylonitrile Nanofibers; a Biomimetic Wound Healing Material.

Shahin Homaeigohar, Mhd Adel Assad, Amir Hossein Azari, Farnaz Ghorbani, Chloe Rodgers, Matthew J Dalby, Kai Zheng, Rongyao Xu, Mady Elbahri, Aldo R Boccaccini

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS applied bio materials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Apoptosis and Cell Clearance in Skin Wound Healing.Advances in experimental medicine and biology · 2025
    Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shahin HomaeigoharSchool of Science and Engineering, University of Dundee, Dundee DD1 4HN, U.K.ORCID 0000-0003-2426-6690
Mhd Adel AssadNanochemistry and Nanoengineering, Department of Chemistry and Materials Science, School of Chemical Engineering, Aalto University, Espoo 02150, Finland.
Amir Hossein AzariNanochemistry and Nanoengineering, Department of Chemistry and Materials Science, School of Chemical Engineering, Aalto University, Espoo 02150, Finland.
Farnaz GhorbaniInstitute of Biomaterials, Department of Materials Science and Engineering, University of Erlangen-Nuremberg, Erlangen 91058, Germany.
Chloe RodgersCentre for the Cellular Microenvironment, University of Glasgow, Glasgow 11 6EW, U.K.ORCID 0000-0002-0046-3406
Matthew J DalbyCentre for the Cellular Microenvironment, University of Glasgow, Glasgow 11 6EW, U.K.ORCID 0000-0002-0528-3359
Kai ZhengJiangsu Province Engineering Research Center of Stomatological Translational Medicine, Nanjing Medical University, Nanjing 210029, China.
Rongyao XuJiangsu Province Engineering Research Center of Stomatological Translational Medicine, Nanjing Medical University, Nanjing 210029, China.
Mady ElbahriNanochemistry and Nanoengineering, Department of Chemistry and Materials Science, School of Chemical Engineering, Aalto University, Espoo 02150, Finland.
Aldo R BoccacciniInstitute of Biomaterials, Department of Materials Science and Engineering, University of Erlangen-Nuremberg, Erlangen 91058, Germany.ORCID 0000-0002-7377-2955

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multifunctional biohybrid nanofibers (NFs) that can simultaneously drive various cellular activities and confer antibacterial properties are considered desirable in producing advanced wound healing materials. In this study, a bionanohybrid formulation was processed as a NF wound dressing to stimulate the adhesion and proliferation of fibroblast and endothelial cells that play a major role in wound healing. Polyacrylonitrile (PAN) electrospun NFs were hydrolyzed using NaOH and biofunctionalized with l-carnosine (CAR), a dipeptide which could later biosynthesize zinc oxide (ZnO) nanoparticles (NPs) on the NFs surface. The morphological study verified that ZnO NPs are uniformly distributed on the surface of CAR/PAN NFs. Through EDX and XRD analysis, it was validated that the NPs are composed of ZnO and/or ZnO/Zn(OH)

Indexed as

CarnosineNanofibersNanoparticlesZinc OxideAcrylic ResinsAnti-Bacterial AgentsBiomimeticsEndothelial CellsStaphylococcus aureusWound HealingAcrylic ResinsAnti-Bacterial AgentsCarnosinepolyacrylonitrileZinc Oxidebiofunctionalizationl-carnosinenanofiberpolyacrylonitrilewound healingzinc oxide

Identifiers

PMID37721636
PMCPMC10583230

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.