Evidence map›Paper›PMID 37721458›Full record

ReviewNutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition2023

Human milk fortification and use of infant formulas to support growth in the neonatal intensive care unit.

Denise H Moreira, Sarah B Gregory, Noelle E Younge

Open access · greenAbstract readReview
In one paragraph

Review in Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. The fifty billion dollar question: does formula cause necrotizing enterocolitis?Journal of perinatology : official journal of the California Perinatal Association · 2025
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Denise H MoreiraDepartment of Pediatrics, Division of Neonatology, Duke University School of Medicine, Durham, North Carolina, USA.
Sarah B GregoryDepartment of Pediatrics, Division of Neonatology, Duke University School of Medicine, Durham, North Carolina, USA.
Noelle E YoungeDepartment of Pediatrics, Division of Neonatology, Duke University School of Medicine, Durham, North Carolina, USA.ORCID http://orcid.org/0000-0001-7829-0608
Duke University · US

Funding

The Microbiome and Metabolism in Postnatal Growth FailureK23DK120960 · NIDDK · DUKE UNIVERSITY · PI YOUNGE, NOELLE ELIZABETH · 2019 to 2022
$874k
NIDDK NIH HHS K23 DK120960
6 · The paper itself

Abstract

Newborn infants require adequate nutrition to achieve full potential growth and development. Early life nutrition and health impacts long-term outcomes through adulthood. Human milk is the optimal source of nutrition during the first 6 months of life. However, infants admitted to the neonatal intensive care unit (NICU) often have comorbidities that create more or different nutrition demands than healthy newborns. There are different strategies to meet the nutrition needs of sick newborns, including use of parenteral nutrition, human milk fortifiers (HMFs), and infant formulas. Multinutrient HMFs are frequently used to achieve the higher nutrition demands of preterm infants. They are available in various presentations, such as human milk- or cow milk-derived, liquid or powder, and acidified or nonacidified, each of which has different risks and benefits associated with its use. Infant formulas are available to meet a demand when mother's own milk or donor breast milk is not available or sufficient, and there are also specialty formulas for infants with certain diseases that present unique nutrition needs. This review is focused on the use of HMFs to support the unique nutrition requirements of preterm infants for healthy growth, as well as the indications for the use of formulas among infants in the NICU.

Indexed as

Infant FormulaMilk, HumanAnimalsCattleFemaleHumansInfantInfant, NewbornInfant, PrematureIntensive Care Units, NeonatalNutritional Statushuman milkhuman milk fortifiersneonatal intensive care unitnewborn infant

Identifiers

PMID37721458
PMCPMC10662944
OpenAlexW4386818233

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.