Evidence map›Paper›PMID 37721046›Full record

ArticleHypertension (Dallas, Tex. : 1979)2023

Sleeping Difficulties, Sleep Duration, and Risk of Hypertension in Women.

Shahab Haghayegh, Susanne Strohmaier, Rikuta Hamaya, A Heather Eliassen, Walter C Willett, Eric B Rimm, Eva S Schernhammer

Open access · greenAbstract read
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
9.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Associations between insomnia and cardiovascular diseases: a meta-review and meta-analysis of observational and Mendelian randomization studies.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024
    Pooled it
  2. Review
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  7. The association between obstructive sleep apnea risk and cardiovascular disease risk in midlife Thai women in the U.S.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026
    Article
  8. Article
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  10. Brazilian Guidelines of Hypertension - 2025.Arquivos brasileiros de cardiologia · 2025
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  14. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Shahab HaghayeghChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (S.H., S.S., A.H.E., E.B.R., E.S.S.).
Susanne StrohmaierChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (S.H., S.S., A.H.E., E.B.R., E.S.S.).ORCID 0000-0002-9387-2056
Rikuta HamayaDepartments of Epidemiology (R.H., A.H.E., W.C.W., E.B.R., E.S.S.), Harvard T.H. Chan School of Public Health, Boston, MA.
A Heather EliassenChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (S.H., S.S., A.H.E., E.B.R., E.S.S.).
Walter C WillettDepartments of Epidemiology (R.H., A.H.E., W.C.W., E.B.R., E.S.S.), Harvard T.H. Chan School of Public Health, Boston, MA.ORCID 0000-0003-1458-7597
Eric B RimmChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (S.H., S.S., A.H.E., E.B.R., E.S.S.).ORCID 0000-0002-1402-7250
Eva S SchernhammerChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (S.H., S.S., A.H.E., E.B.R., E.S.S.).ORCID 0000-0002-4337-9415
Brigham and Women's Hospital · USHarvard University · US

Funding

Statistical MethodsP01CA087969 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI ROSNER, BERNARD A · 2000 to 2019
$77.8M
Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI JAIME ELIZABETH HART · 1985 to 2026
$44.6M
Life Course Cancer Epidemiology Cohort in WomenU01CA176726 · NCI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI ELIASSEN, A. HEATHER, WILLETT, WALTER C. · 2018 to 2025
$22.4M
Long Term Multidisciplinary Study of Cancer in Women: The Nurses Health StudyUM1CA186107 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI ELIASSEN, A. HEATHER, STAMPFER, MEIR · 2014 to 2023
$22.3M
Integrating lifecourse approaches, biologic and digital phenotypes in support of heart and lung disease epidemiologic researchU01HL145386 · NHLBI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI CHAVARRO, JORGE EDUARDO, MANSON, JOANN ELISABETH · 2019 to 2025
$17.8M
Mechanistic pathways of the effects of human-animal interaction on depression and psychosocial stressR01HD101101 · NICHD · BRIGHAM AND WOMEN'S HOSPITAL · PI SCHERNHAMMER, EVA S · 2020 to 2025
$3.6M
Psychological stress, associate biologic mediators, and ovarian cancer riskR01CA163451 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI TWOROGER, SHELLEY S · 2012 to 2015
$1.7M
NCI NIH HHS P01 CA087969NCI NIH HHS R01 CA163451NCI NIH HHS U01 CA176726NCI NIH HHS UM1 CA186107NHLBI NIH HHS U01 HL145386NICHD NIH HHS R01 HD101101NIEHS NIH HHS P30 ES000002
6 · The paper itself

Abstract

backgroundRates of poor sleep and hypertension are alarming worldwide. In this study, we investigate the association between sleeping difficulties and sleep duration with hypertension risk in women.

methodsSixty-six thousand one hundred twenty-two participants of the Nurses' Health Study 2, who were free of hypertension at baseline (2001), were followed prospectively for 16 years and incident hypertension assessed every 2 years. Cox proportional hazards models were used to estimate hazard ratios (HRs) and 95% confidence intervals (95% CIs) for hypertension incidence associated with sleeping difficulties and sleep duration.

resultsDuring follow-up, we documented 25 987 incident cases of hypertension. After controlling for demographic and lifestyle risk factors, compared with women who slept 7 to 8 hours, women with shorter sleep duration had a significantly higher risk of hypertension (≤5 hours: HR, 1.10 [95% CI, 1.05-1.16]; 6 hours: HR, 1.07 [95% CI, 1.03-1.10]), whereas the risk for women with longer sleep duration was not statistically significant (9 hours: HR, 1.03 [95% CI, 0.97-1.10]; >9 hours: HR, 1.08 [95% CI, 0.94-1.23]). Compared with women rarely having difficulty falling or staying asleep, women sometimes or usually having these sleep difficulties had significantly higher risk of developing hypertension (HR, 1.14 [95% CI, 1.11-1.17] and 1.28 [95% CI, 1.22-1.35];

conclusionsDifficulty falling or staying asleep and short sleep duration were associated with higher risk of hypertension among women in our study. Screening for poor sleep could be useful in identifying people at higher risk for hypertension.

Indexed as

HypertensionSleep Initiation and Maintenance DisordersSleep Wake DisordersCohort StudiesFemaleHumansRisk FactorsSleepSleep Durationblood pressurechronotypehypertensionsleep durationsleep initiation and maintenance disorders

Identifiers

PMID37721046
PMCPMC10591959
OpenAlexW4386818203

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.