Evidence map›Paper›PMID 37720991›Full record

ArticlePhysiological genomics2023

Polycystin-2-dependent transcriptome reveals early response of autosomal dominant polycystic kidney disease.

Hyun Jun Jung, Eryn E Dixon, Richard Coleman, Terry Watnick, Jeremy F Reiter, Patricia Outeda, Valeriu Cebotaru, Owen M Woodward, Paul A Welling

Open access · greenAbstract read
In one paragraph

Article in Physiological genomics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Glis3 Is a Modifier of Cyst Progression in Autosomal Dominant Polycystic Kidney Disease.Journal of the American Society of Nephrology : JASN · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Hyun Jun JungDivision of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States.ORCID 0000-0003-0519-5858
Eryn E DixonDepartment of Physiology, University of Maryland School of Medicine, Baltimore, Maryland, United States.ORCID 0000-0003-4604-7907
Richard ColemanDivision of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States.
Terry WatnickDivision of Nephrology, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States.
Jeremy F ReiterDepartment of Biochemistry and Biophysics, University of California, San Francisco, California, United States.
Patricia OutedaDivision of Nephrology, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States.
Valeriu CebotaruDivision of Nephrology, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States.
Owen M WoodwardDepartment of Physiology, University of Maryland School of Medicine, Baltimore, Maryland, United States.ORCID 0000-0001-9514-2180
Paul A WellingDivision of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States.ORCID 0000-0002-0719-8705
University of Maryland, Baltimore · USJohns Hopkins University · USUniversity of California, San Francisco · US

Funding

Hedgehog signaling at the cell's antenna: Smoothened and the primary ciliumR01AR054396 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Jeremy F Reiter · 2007 to 2026
$9.0M
PKD Innovation and Resource Development CoreU54DK126114 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI Feng Qian · 2020 to 2026
$7.3M
Transition zone control of ciliary signalingR01DE029454 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI REITER, JEREMY F · 2019 to 2022
$2.3M
NIAMS NIH HHS R01 AR054396NIDCR NIH HHS R01 DE029454NIDDK NIH HHS U54 DK126114
6 · The paper itself

Abstract

Autosomal dominant polycystic kidney disease (ADPKD) is caused by mutations in polycystin genes,

Indexed as

CystsPolycystic Kidney, Autosomal DominantAnimalsMiceMice, KnockoutTranscriptomeTRPP Cation ChannelsTRPP Cation Channelsautosomal dominant polycystic kidney diseasecystogenesisin vitro cell modelpolycystin-2RNA sequencing

Identifiers

PMID37720991
PMCPMC11178268
OpenAlexW4386817691

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.