Evidence map›Paper›PMID 37720854›Full record

ArticleTurkish journal of chemistry2023

Electrochemical determination of aripiprazole based on aluminium oxide nanoparticles modified carbon paste electrode.

Funda Öztürk, Elif Yüksel, Pınar Esra Erden, Esma Kiliç

Abstract read
In one paragraph

Article in Turkish journal of chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Funda ÖztürkDepartment of Chemistry, Faculty of Science and Arts, Tekirdağ Namık Kemal University, Tekirdağ, Turkey.ORCID https://orcid.org/0000-0001-8612-380X
Elif YükselDepartment of Chemistry, Faculty of Science and Arts, Tekirdağ Namık Kemal University, Tekirdağ, Turkey.ORCID https://orcid.org/0000-0003-1198-2129
Pınar Esra ErdenDepartment of Chemistry, Polatlı Faculty of Science and Letters, Ankara Hacı Bayram Veli University, Ankara, Turkey.ORCID https://orcid.org/0000-0001-5153-8319
Esma KiliçDepartment of Chemistry, Faculty of Science, Ankara University, Ankara, Turkey.ORCID https://orcid.org/0000-0003-3953-3421

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The electrochemical oxidation of aripiprazole was explored at a carbon paste electrode modified with aluminium oxide nanoparticles by cyclic voltammetry and square-wave anodic adsorptive stripping voltammetry. Experimental parameters such as carbon paste composition, scan rate, buffer pH, accumulation time, and accumulation potential were optimized in order to obtain high analytical performance. The incorporation of aluminium oxide nanoparticles into the carbon paste matrix enhanced the effective surface area of the carbon paste electrode and improved the sensitivity. On the aluminium oxide nanoparticles modified carbon paste electrode, aripiprazole exhibited an irreversible anodic peak at +1.17 V in pH 1.8 BR buffer solution. Under optimum conditions, the peak current exhibited a linear dependence with aripiprazole concentration between 0.03 and 8.0 μM with a detection limit of 0.006 μM. The analytical applicability of the voltammetric method was evaluated by quantification of ARP in human serum samples and pharmaceutical formulations.

Indexed as

aluminium oxide nanoparticlesAripiprazolebiological fluidcarbon paste electrodepharmaceutical formulationsquare wave voltammetry

Identifiers

PMID37720854
PMCPMC10504013

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.