Evidence map›Paper›PMID 37720849›Full record

ArticleTurkish journal of chemistry2023

Investigating the effect of poly (ɛ-caprolactone) nanofibers scaffolds with random, unidirectionally, and radially aligned morphologies on the Fibroblast cell's attachment and growth behavior.

Saeed Nezari, Mohammadamin Sarli, Ahmad Hivechi, S Hajir Bahrami, Peiman B Milan, Noorahmad Latifi, Fatemeh Latifi, Tayyeb Ghadimi, S Mohammad Amin Haramshahi, Soheila Naderi Gharahgheshlagh

Abstract read
In one paragraph

Article in Turkish journal of chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Saeed NezariDepartment of Textile Engineering, Amirkabir University of Technology, Tehran, Iran.ORCID https://orcid.org/0000-0001-8399-778X
Mohammadamin SarliDepartment of Textile Engineering, Ege University, İzmir, Turkey.ORCID https://orcid.org/0000-0002-1013-4147
Ahmad HivechiDepartment of Textile Engineering, Amirkabir University of Technology, Tehran, Iran.ORCID https://orcid.org/0000-0002-3879-0998
S Hajir BahramiDepartment of Textile Engineering, Amirkabir University of Technology, Tehran, Iran.ORCID https://orcid.org/0000-0001-5777-8428
Peiman B MilanCellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0002-3602-2960
Noorahmad LatifiDepartment of Textile Engineering, Amirkabir University of Technology, Tehran, Iran.ORCID https://orcid.org/0000-0002-6023-9270
Fatemeh LatifiDepartment of Oral and Maxillofacial Surgery, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0001-9867-1643
Tayyeb GhadimiDepartment of Plastic and Reconstructive Surgery, Hazrat Fatemeh Hospital, Iran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0002-1473-0149
S Mohammad Amin HaramshahiCellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0002-8183-1548
Soheila Naderi GharahgheshlaghDepartment of Plastic and Reconstructive Surgery, Hazrat Fatemeh Hospital, Iran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0003-4935-0995

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the last decade, significant progress in tissue engineering, repairing, and replacing organs has been achieved. The design and production of scaffolds for tissue engineering are one of the main areas which have attracted the researcher's interest. In this regard, electrospinning is one of the most popular methods of nanoscale scaffold similar to extracellular matrix production. This paper reports the fabrication of scaffolds consisting of radially aligned PCL nanofibers by utilizing a collector composed of a central point electrode and a peripheral ring electrode. The chemical and physical properties were compared using SEM, FTIR, XRD, and DSC experiments, as well as biological performance using the MTT method and cell morphology with nanofibers with random and unidirectionally morphology. Results of this study showed greater physical and biological properties for radially aligned nanofibers which make them an excellent candidate for wound healing applications due to the guided cell growth on this type of nanofiber.

Indexed as

biomaterialsmorphologyNanofibertissue engineering

Identifiers

PMID37720849
PMCPMC10503997

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.