ArticleResearch square2023
The PML1-WDR5 axis regulates H3K4me3 marks and promotes stemness of estrogen receptor-positive breast cancer.
Hung-Ying Kao, Chun-Peng Pai, Han Wang, Neel Agarwal, Joshua Adams, Zhenghao Liu, Darcie Seachrist, Ruth Keri, William Schiemann
Open access · greenAbstract readPreprint
In one paragraphArticle in Research square, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 2 citations in OpenAlex.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
9 authors at 1 institution in 1 country.
Hung-Ying KaoCase Western Reserve University.
Chun-Peng PaiCase Western Reserve University (CWRU).
Han WangCase Western Reserve University.
Neel AgarwalCase Western Reserve University.
Zhenghao LiuCase Western Reserve University.
Darcie SeachristCleveland Clinic Lerner Research Institute.
Ruth KeriCleveland Clinic Lerner Research Institute.
William SchiemannCase Western Reserve University.
Washington University in St. Louis · US
Funding
TUMOR METABOLISM PROGRAMP30CA043703 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI Amar Desai · 1987 to 2026
$142.3MCancer-focused Summer Undergraduate Research (CanSUR) ProgramR25CA225461 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI MARK W. JACKSON · 2018 to 2026
$2.8MSupplement - Discovering the role of YES1 in triple negative breast cancerR01CA257502 · NCI · CLEVELAND CLINIC LERNER COM-CWRU · PI KERI, RUTH A. · 2021 to 2025
$2.8MRole of the lncRNA BORG in Breast Cancer Metastatic Progression and RecurrenceR01CA236273 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI SCHIEMANN, WILLIAM, VALADKHAN, SABA · 2019 to 2023
$2.3MElucidating and Leveraging the mTOR Negative Feedback Pathway in Breast CancerR01CA213843 · NCI · CLEVELAND CLINIC LERNER COM-CWRU · PI KERI, RUTH A. · 2017 to 2021
$2.0MTargeting BET proteins in Triple Negative Breast CancerR01CA206505 · NCI · CLEVELAND CLINIC LERNER COM-CWRU · PI KERI, RUTH A. · 2016 to 2020
$1.8MNCI NIH HHS P30 CA043703NCI NIH HHS R01 CA206505NCI NIH HHS R01 CA213843NCI NIH HHS R01 CA236273NCI NIH HHS R01 CA257502NCI NIH HHS R25 CA225461
6 · The paper itselfAbstract
The alternative splicing of
Indexed as
breast cancer stemnessestrogen receptor-positive breast cancerhistone 3 lysine 4 trimethylation (H3K4me3)Promyelocytic leukemia protein (PML)transcriptional regulation
Identifiers
PMID37720048
PMCPMC10503857
OpenAlexW4386533005
What OpenQuestion holds
Textmetadata
LicenceCC BY
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