Evidence map›Paper›PMID 37720026›Full record

ArticleResearch square2023

Role of NLRP3 inflammasomes in monocyte and microglial recruitments in choroidal neovascularization.

Blake W Dieckmann, Marcell E Paguaga, Gary W McCollum, John S Penn, Imam Uddin

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Blake W DieckmannVanderbilt University School of Medicine.
Marcell E PaguagaVanderbilt University School of Medicine.
Gary W McCollumVanderbilt University School of Medicine.
John S PennVanderbilt University School of Medicine.
Imam UddinVanderbilt University Medical Center.
Vanderbilt University · USVanderbilt University Medical Center · US

Funding

Shop Module CoreP30EY008126 · NEI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI David J. Calkins · 1989 to 2026
$19.6M
In Vivo Molecular Imaging of the RetinaR01EY023397 · NEI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PENN, JOHN S., UDDIN, MD IMAM · 2013 to 2022
$3.6M
In Vivo Molecular Imaging of Vascular Disease of the RetinaR01EY029693 · NEI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI UDDIN, MD IMAM · 2019 to 2023
$2.1M
NEI NIH HHS P30 EY008126NEI NIH HHS R01 EY023397NEI NIH HHS R01 EY029693
6 · The paper itself

Abstract

Though the pathogenesis of choroidal neovascularization (CNV) is largely unknown in age-related macular degeneration (AMD), inflammasomes may contribute to CNV development and progression. To understand the role NLRP3 inflammasomes in CNV, we used

Indexed as

Age-related macular degenerationlaser-induced choroidal neovascularizationmacrophageMCC950microgliamonocyteNLRP3 inflammasomeNLRP3 inhibitor

Identifiers

PMID37720026
PMCPMC10503854
OpenAlexW4386532022

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.