Evidence map›Paper›PMID 37720000›Full record

ArticleObstetric medicine2023

Maternal health and pregnancy outcomes in autosomal dominant tubulointerstitial kidney disease.

Anthony J Bleyer, Kendrah O Kidd, Adrienne H Williams, Emily Johnson, Victoria Robins, Lauren Martin, Abbigail Taylor, Alice Kim, Isai Bowline, Dervla M Connaughton and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Obstetric medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Obstetric medicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Anthony J BleyerSection on Nephrology, Wake Forest School of Medicine, Winston-Salem, NC, USA.ORCID https://orcid.org/0000-0002-2804-5273
Kendrah O KiddSection on Nephrology, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Adrienne H WilliamsDNA Data Solutions, LLC, St. Petersburg, FL, USA.
Emily JohnsonDivision of Public Health Sciences, Department of Biostatistics and Data Science, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Victoria RobinsSection on Nephrology, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Lauren MartinSection on Nephrology, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Abbigail TaylorSection on Nephrology, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Alice KimSection on Nephrology, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Isai BowlineSection on Nephrology, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Dervla M ConnaughtonSchulich School of Medicine and Dentistry, University of Western Ontario, ON, Canada.
Carl D LangefeldDivision of Public Health Sciences, Department of Biostatistics and Data Science, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Martina ZivnaResearch Unit of Rare Diseases, Department of Paediatrics and Inherited Metabolic Disorders, First Faculty of Medicine, Charles University, Prague, Czech Republic.
Stanislav KmochSection on Nephrology, Wake Forest School of Medicine, Winston-Salem, NC, USA.

Funding

Chronic Kidney Disease (CKD) Biomarkers Consortium Data Coordinating CenterU01DK103225 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI SCHRAUBEN, SARAH JEANNE · 2014 to 2020
$5.5M
Genetic Variation in Age of Onset of Kidney Failure in Uromodulin Kidney DiseaseR21DK106584 · NIDDK · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI BLEYER, ANTHONY J · 2015 to 2016
$426k
NIDDK NIH HHS R21 DK106584NIDDK NIH HHS U01 DK103225
6 · The paper itself

Abstract

Introduction: Autosomal dominant tubulointerstitial kidney disease (ADTKD) is an increasingly recognized cause of chronic kidney disease. ADTKD pregnancy outcomes have not previously been described. Methods: A cross-sectional survey was sent to women from ADTKD families. Results: Information was obtained from 85 afffected women (164 term pregnancies) and 23 controls (50 pregnancies). Only 16.5% of genetically affected women knew they had ADTKD during pregnancy. Eighteen percent of ADTKD mothers had hypertension during pregnancy versus 12% in controls ( Conclusions: ADTKD pregnancies had lower rates of hypertension during pregnancy versus other forms of chronic kidney disease, which may have contributed to good maternal and fetal outcomes.

Indexed as

autosomal dominant tubulointerstitial kidney diseaseepidemiologyMaternal healthMUC1pregnancyUMOD

Identifiers

PMID37720000
PMCPMC10504889

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.