ArticleFrontiers in clinical diabetes and healthcare2023
Incidence and predictors of mortality in children with diabetic ketoacidosis in the comprehensive specialized referral hospitals of West Amhara Region, Northwest Ethiopia: a retrospective follow-up study.
Article in Frontiers in clinical diabetes and healthcare, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Adverse Outcomes and Associated Factors Among Children and Youths With Diabetes Mellitus in East Africa: A Systematic Review and Meta-Analysis.Journal of advanced nursing · 2026Pooled it
- Determinants of diabetic ketoacidosis among adults with diabetes mellitus at the Ambo town Hospitals, Ethiopia.Scientific reports · 2025Article
- The incidence of cerebral edema in pediatric patients with diabetic ketoacidosis: a retrospective study.BMC research notes · 2025Article
- Incidence and Predictors of Diabetic Keto-acidosis Among Children Under 15 Years At Central Ethiopia Public Hospital A Retrospective Cohort Study.Clinical medicine insights. Pediatrics · 2025Article
- Clinical significance of pyuria in pediatric diabetic ketoacidosis: evidence against empirical antibiotic use.Pediatric endocrinology, diabetes, and metabolism · 2025Observational
- Innovations and applications of ketone body monitoring in diabetes care.Diabetology international · 2024Review
- Hypoglycemia during hyperosmolar hyperglycemic crises is associated with long-term mortality.Diabetology & metabolic syndrome · 2024Article
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Abstract
Background: Diabetic ketoacidosis is one of the major life-threatening conditions associated with acute metabolic complications. It remains a major public health problem in developing countries such as Ethiopia. Objective: To assess the incidence and prediction of mortality in children with diabetic ketoacidosis in West Amhara Region Comprehensive Specialized Referral Hospitals, Northwest Ethiopia, in 2022. Methods: An institution-based retrospective follow-up study was conducted among 423 study participants with a confirmed diagnosis of diabetic ketoacidosis from 01/01/2017 to 31/12/2021. Data were entered, coded, cleaned, and checked using Epi-Data version 4.6 and exported to Stata version 14 for data analysis. Results: A total of 401 child records were included in the final analysis and were followed for 3781 days during the study period. The overall mortality of children with diabetic ketoacidosis was 10.6 per 1000 person-days observed (95% CI: 7.8-14.4) during the entire follow-up period. Hypoglycemia (AHR=4.6; 95% CI: 2.13-10.1), rural residence (AHR=2.9; 95% CI=1.01-8.11), age younger than five (AHR=4.4; 95% CI=1.4-13.7) or between five and 10 (AHR=3.1; 95% CI=1.1-8.8), and female gender (AHR=2.6; 95% CI=1.1-5.8) were significant predictors of mortality. Conclusions: The incidence rate of mortality in children with diabetic ketoacidosis was relatively high. Age, rural residence, female gender, and hypoglycemia were significantly predictive of mortality. Community education or mass campaigns about the signs and symptoms of diabetic ketoacidosis may reduce the mortality rate in children.
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