Evidence map›Paper›PMID 37719966›Full record

ArticleJournal of clinical and translational hepatology2023

Prognostic Performance of the China Liver Cancer Staging System in Hepatocellular Carcinoma Following Transarterial Chemoembolization.

Bin-Yan Zhong, Jian-Qiang Jiang, Jun-Hui Sun, Jin-Tao Huang, Wei-Dong Wang, Qi Wang, Wen-Bin Ding, Xiao-Li Zhu, Cai-Fang Ni

Abstract read
In one paragraph

Article in Journal of clinical and translational hepatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Bin-Yan ZhongDepartment of Interventional Radiology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.ORCID https://orcid.org/0000-0001-9716-1211
Jian-Qiang JiangDepartment of Interventional Therapy, Nantong Tumor Hospital, Nantong, Jiangsu, China.
Jun-Hui SunHepatobiliary and Pancreatic Interventional Treatment Center, Division of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Jin-Tao HuangDepartment of Interventional Radiology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Wei-Dong WangDepartment of Interventional Radiology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.
Qi WangDepartment of Interventional Radiology, Third Affiliated Hospital of Soochow University, Changzhou First Hospital, Changzhou, Jiangsu, China.
Wen-Bin DingDepartment of Interventional Radiology, Nantong First People's Hospital, Nantong, Jiangsu, China.
Xiao-Li ZhuDepartment of Interventional Radiology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Cai-Fang NiDepartment of Interventional Radiology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.ORCID https://orcid.org/0000-0002-3371-3854

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: To validate prognostic performance of the China liver cancer (CNLC) staging system as well as to compare these parameters with those of the Barcelona Clinic Liver Cancer (BCLC) staging system for Chinese hepatocellular carcinoma (HCC) treated with transarterial chemoembolization (TACE). Methods: This multicenter retrospective study included 1,124 patients with HCC between January 2012 and December 2020 from six Chinese hospitals. Based on overall survival (OS), the prognostic performance outcomes for the CNLC and BCLC staging systems were compared by model discrimination [C statistic and Akaike information criterion (AIC)], monotonicity of the gradient (linear trend chi-square test), homogeneity (likelihood ratio chi-square test), and calibration (calibration plots). A prospective cohort of 44 patients receiving TACE-based therapy included between January 2021 and December 2022 was used to prospectively validate the outcomes. Results: Median OS was 19.1 (18.2-20.0) months, with significant differences in OS between stages defined by the CNLC and BCLC observed ( Conclusions: Combining model discrimination, gradient monotonicity, homogeneity, and calibration, the CNLC performed better than the BCLC for Chinese HCC patients receiving TACE.

Indexed as

BCLCCNLCHepatocellular carcinomaTACE

Identifiers

PMID37719966
PMCPMC10500297

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.