Evidence map›Paper›PMID 37719935›Full record

ReviewClinical, cosmetic and investigational dermatology2023

Congenital Ichthyosis: A Practical Clinical Guide on Current Treatments and Future Perspectives.

Evelyn Lilly, Christopher G Bunick

Abstract readReview
In one paragraph

Review in Clinical, cosmetic and investigational dermatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Evelyn LillyDepartment of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA.ORCID 0000-0001-5387-0569
Christopher G BunickDepartment of Dermatology and Program in Translational Biomedicine, Yale School of Medicine, New Haven, CT, 06520, USA.ORCID 0000-0002-4011-8308

Funding

Molecular function of an intermediate filament assembly mechanism in epidermal protein complexes and cell migrationR01AR079428 · NIAMS · YALE UNIVERSITY · PI BUNICK, CHRISTOPHER GERARD · 2021 to 2025
$1.8M
NIAMS NIH HHS R01 AR079428
6 · The paper itself

Abstract

Congenital ichthyoses are a group of hereditary disorders of keratinization that are challenging to treat. Affected individuals suffer not only from thickening of the skin but also associated complications such as growth restriction, hearing and eye complications, infections, and thermodysregulation. This clinical review provides a practical roadmap to the longitudinal care of patients with ichthyosis with both general and age- and disease-specific recommendations. The allure of pathogenesis-based and targeted treatments for these monogenetic severe but orphan conditions shines bright as dermatological therapies enter a new era.

Indexed as

clinical managementcutaneous diseasegenetic mutationJAK and TYK2 inhibitorsretinoidsskin caretopical and oral therapy

Identifiers

PMID37719935
PMCPMC10503504

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.