Evidence map›Paper›PMID 37719677›Full record

ArticleBiomedical reports2023

Serum vitamin D status in a cohort of infants with food protein‑induced gastrointestinal disease.

Meng-Yao Zhou, Xin Li, Jing Yang, Li-Jing Xiong, Xiao-Qing He, Xiao-Qing He, Xiao-Li Xie

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Article in Biomedical reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Meng-Yao ZhouDepartment of Pediatric Infection and Gastroenterology, Chengdu Women and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology, Chengdu, Sichuan 611731, P.R. China.
Xin LiDepartment of Pediatric, University of Electronic Science and Technology, Chengdu, Sichuan 610000, P.R. China.
Jing YangDepartment of Pediatric Infection and Gastroenterology, Chengdu Women and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology, Chengdu, Sichuan 611731, P.R. China.
Li-Jing XiongDepartment of Pediatric Healthcare, Chengdu Women and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology, Chengdu, Sichuan 611731, P.R. China.
Xiao-Qing HeDepartment of Pediatric Infection and Gastroenterology, Chengdu Women and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology, Chengdu, Sichuan 611731, P.R. China.
Xiao-Qing HeDepartment of Pediatric Infection and Gastroenterology, Chengdu Women and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology, Chengdu, Sichuan 611731, P.R. China.
Xiao-Li XieDepartment of Pediatric Infection and Gastroenterology, Chengdu Women and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology, Chengdu, Sichuan 611731, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increases in the prevalence of food allergy and vitamin D deficiency have been observed in recent years. The association between vitamin D levels and food allergy remains to be fully elucidated, and research focused on the prevalence of vitamin D insufficiency in infants with food protein-induced gastrointestinal disease in Chengdu, Sichuan is lacking. Thus, the present study aimed to determine the prevalence and clinical characteristics of serum 25 hydroxyvitamin D [25-(OH)D] insufficiency and sufficiency in infants with food protein-induced gastrointestinal disease. The present study also aimed to identify the potential predisposing factors of 25-(OH)D insufficiency. The present retrospective study analyzed data obtained from Chengdu Women's and Children's Central Hospital spanning between June 2021 and February 2022. Children with a confirmed diagnosis of food protein-induced gastrointestinal disease were enrolled in the present study. Blood indicators, including serum 25-(OH)D, serum total immunoglobulin E (IgE), specific IgE against allergens, and hemoglobin were measured during the course of the disease. Clinical characteristics of patients and blood examination results were obtained from the hospital electronic database. A total of 361 patients were included in the study group and 45 healthy individuals were included in the control group. The results of the present study demonstrated that serum 25-(OH)D levels of infants with protein-induced gastrointestinal disease were significantly lower compared with the control group. Notably, female participants with higher serum total IgE levels exhibited insufficient serum 25-(OH)D levels. However, the results of the logistic regression analysis revealed no predisposing factors associated with serum 25-(OH)D insufficiency. In conclusion, infants with food protein-induced gastrointestinal disease may exhibit a higher risk of low serum 25-(OH)D levels and this risk may be greater in females with higher total IgE.

Indexed as

25 hydroxy-vitamin Dgastrointestinal food allergyimmunoglobulin Epediatricsvitamin D

Identifiers

PMID37719677
PMCPMC10502572

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