Evidence map›Paper›PMID 37719614›Full record

ReviewCureus2023

Hope in Every Breath: Navigating the Therapeutic Landscape of Cystic Fibrosis.

Himabindu Sreenivasulu, Sudheer Kumar Muppalla, Sravya Vuppalapati, Mohammad Shokrolahi, Apeksha Reddy Pulliahgaru

Abstract readReview
In one paragraph

Review in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Himabindu SreenivasuluGeneral Medicine, People's Education Society (PES) Institute of Medical Sciences and Research, Kuppam, IND.
Sudheer Kumar MuppallaPediatrics, People's Education Society (PES) Institute of Medical Sciences and Research, Kuppam, IND.
Sravya VuppalapatiGeneral Medicine, People's Education Society (PES) Institute of Medical Sciences and Research, Kuppam, IND.
Mohammad ShokrolahiInternal Medicine, University of Debrecen, Debrecen, HUN.
Apeksha Reddy PulliahgaruPediatrics, People's Education Society (PES) Institute of Medical Sciences and Research, Kuppam, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cystic fibrosis (CF) has long posed a complex challenge to medical science. Still, the tides are turning with remarkable progress in prognosis and demographics, thanks to cutting-edge medical management and treatment breakthroughs. It affects multiple systems, necessitating a comprehensive approach to its management. This article thoroughly reviews the latest advancements in CF treatment across three key areas: respiratory care, infection prevention, and pharmacological management. In respiratory care, emphasis is placed on airway clearance therapies and nebulized saline, while infection prevention strategies encompass hand hygiene, respiratory etiquette, and environmental cleaning and disinfection. Pharmacological management explores pancreatic enzyme replacement therapy (PERT), antimicrobial treatments, cystic fibrosis transmembrane regulator (CFTR) modulators, and promising gene therapies. Patient education and support are highlighted as crucial components of effective CF management, while mental health assessments are emphasized due to CF patients' susceptibility to anxiety and depression. This review highlights the tremendous progress made in the management of CF. Integrating early detection, infection prevention, pharmacological interventions, gene therapy, and patient support is revolutionizing the care and quality of life for individuals with CF.

Indexed as

cftr modulating therapychest physiotherapycystic fibrosis (cf)gene therapyhand hygiene complianceinfection prevention and controlpatient educationpulmonary screeningrespiratory care

Identifiers

PMID37719614
PMCPMC10504422

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.