Evidence map›Paper›PMID 37719341›Full record

ArticleIndian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine2023

Xpert Carba-R Assay on Flagged Blood Culture Samples: Clinical Utility in Intensive Care Unit Patients with Bacteremia Caused by

Surendran Rajendran, Ram Gopalakrishnan, Anil Tarigopula, D Suresh Kumar, P Senthur Nambi, Nandini Sethuraman, Chitra Chandran, Nagarajan Ramakrishnan, V Ramasubramanian

Abstract read
In one paragraph

Article in Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. The Novel "RISC" Score as a Risk-prediction Model of Carbapenem-resistant Hospital-acquired Infections in Adult Sepsis Patients - A Prospective Observational Study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2025
    Article
  3. Proportion of carbapenem-resistant Enterobacterales with readily detectable beta-lactam resistance.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025
    Article
  4. Clinical Utility of Blood Culture Identification 2 Panel in Flagged Blood Culture Samples from the Intensive Care Unit of a Tertiary Care Hospital.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Surendran RajendranDepartment of Infectious Diseases, Apollo Hospitals, Chennai, Tamil Nadu, India.ORCID https://orcid.org/0000-0001-7402-5655
Ram GopalakrishnanDepartment of Infectious Diseases, Apollo Hospitals, Chennai, Tamil Nadu, India.ORCID https://orcid.org/0000-0002-2263-1861
Anil TarigopulaDepartment of Molecular Laboratory Services, Apollo Hospitals, Chennai, Tamil Nadu, India.ORCID https://orcid.org/0000-0001-6493-3510
D Suresh KumarDepartment of Infectious Diseases, Apollo Hospitals, Chennai, Tamil Nadu, India.ORCID https://orcid.org/0000-0001-7643-0144
P Senthur NambiDepartment of Infectious Diseases, Apollo Hospitals, Chennai, Tamil Nadu, India.ORCID https://orcid.org/0000-0003-0519-8768
Nandini SethuramanDepartment of Microbiology, Apollo Hospitals, Chennai, Tamil Nadu, India.ORCID https://orcid.org/0000-0002-3803-5511
Chitra ChandranDepartment of Molecular Diagnostics, Apollo Hospitals, Chennai, Tamil Nadu, India.ORCID https://orcid.org/0000-0002-5504-1569
Nagarajan RamakrishnanDepartment of Critical Care Medicine, Apollo Hospitals, Chennai, Tamil Nadu, India.ORCID https://orcid.org/0000-0001-5208-4013
V RamasubramanianDepartment of Infectious Diseases, Apollo Hospitals, Chennai, Tamil Nadu, India.ORCID https://orcid.org/0000-0001-8566-2035

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction and background: Rapid molecular diagnostics to predict carbapenem resistance well before the availability of routine drug sensitivity testing (DST) can serve as an antimicrobial stewardship tool in the context of high rates of Carbapenem-resistant Materials and methods: A retrospective observational study of patients more than 18 years of age on whom Xpert Carba-R (FDA approved for rectal swab specimen) was done on gram-negative bacteria (GNB) flagged blood culture samples, in an Indian intensive care unit between January 2015 and November 2018. We analyzed the performance of Xpert Carba-R in comparison with routine DST. Results: A total of 164 GNBs were isolated from 160 patients. Conclusion: Xpert Carba-R serves as a rapid diagnostic tool for predicting carbapenem resistance in intensive care unit patients with bacteremia caused by How to cite this article: Rajendran S, Gopalakrishnan R, Tarigopula A, Kumar DS, Nambi PS, Sethuraman N,

Indexed as

Antimicrobial stewardshipCarbapenemase detectionCarbapenem-resistant enterobacteriaceaeGram-negative resistanceNovel diagnostics for antimicrobial resistanceRapid molecular diagnosticsXpert Carba-R assay

Identifiers

PMID37719341
PMCPMC10504648

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.