Evidence map›Paper›PMID 37719258›Full record

ArticleNorthern clinics of Istanbul2023

Evaluation of babies with retinopathy of prematurity following intravitreal bevacizumab administration.

Ozlem Sahin, Aysun Boga, Gulay Karakus Hacioglu, Hatice Gulhan Sozen, Leyla Karadeniz Bilgin

Abstract read
In one paragraph

Article in Northern clinics of Istanbul, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ozlem SahinNeonatal Intensive Care Unit, University of Health Sciences, Umraniye Training and Research Hospital, Istanbul, Turkiye.
Aysun BogaDepartment of Pediatrics, Sancaktepe Sehit Prof. Dr. Ilhan Varank Training and Research Hospital, Istanbul, Turkiye.
Gulay Karakus HaciogluDepartment of Ophthalmology, University of Health Sciences, Umraniye Training and Research Hospital, Istanbul, Turkiye.
Hatice Gulhan SozenDepartment of Pediatric Neurology, Bahcesehir University Faculty of Medicine, Istanbul, Turkiye.
Leyla Karadeniz BilginNeonatal Intensive Care Unit, Istanbul University Faculty of Medicine, Istanbul, Turkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveIn Turkiye, the increased likelihood of survival of small premature babies has resulted in a higher incidence of retinopathy of prematurity (ROP), which causes severe visual impairment in childhood. Early diagnosis and timely and proper treatment of ROP can prevent vision loss. This paper discusses cases of ROP treated with bevacizumab.

methodsPatients treated with bevacizumab for ROP were evaluated retrospectively. Systolic and diastolic blood pressure values were recorded 1 day before and 2 weeks after bevacizumab administration. The Bayley III test, hearing test, eye examination, and neurological evaluation were performed.

resultsThe mean composite Bayley III test scores for cognition, language, motor, social-emotional, and adaptive domains in 10 patients who received bevacizumab for ROP were 75±10.8, 73.4±15.4, 71.2±10.2, 88±23.7, and 65.4±13.8, respectively. The mean values of the day before the injection and the values of the 14 days after the injection were compared, it was seen that there was a significant increase in systolic blood pressure values, especially at the end of 1

conclusionCaution needs attention in the care of neonates until further studies of the long-term benefits and effects of bevacizumab therapy are completed.

Indexed as

Bevacizumabnewbornretinopathy of prematurity

Identifiers

PMID37719258
PMCPMC10500235

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