Evidence map›Paper›PMID 37719231›Full record

ArticleMicrofluidics and nanofluidics2023

Maximizing flow rate in single paper layer, rapid flow microfluidic paper-based analytical devices.

Iain Macleod Briongos, Zachary D Call, Charles S Henry, David L Bark

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microfluidics and nanofluidics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Iain Macleod BriongosSchool of Biomedical Engineering, Colorado State University, Fort Collins, CO 80523 USA.ORCID 0000-0002-6583-348X
Zachary D CallDepartment of Chemistry, Colorado State University, Fort Collins, CO 80523 USA.
Charles S HenryDepartment of Chemistry, Colorado State University, Fort Collins, CO 80523 USA.ORCID 0000-0002-8671-7728
David L BarkSchool of Biomedical Engineering, Colorado State University, Fort Collins, CO 80523 USA.ORCID 0000-0002-9865-6176

Funding

Impact of turbulence on blood in mechanical circulatory supportR01HL164424 · NHLBI · WASHINGTON UNIVERSITY · PI Matthew Kipper · 2022 to 2026
$2.0M
Paper-based high shear hemostatic analytical deviceR21EB034579 · NIBIB · WASHINGTON UNIVERSITY · PI BARK, DAVID · 2023 to 2024
$431k
NHLBI NIH HHS R01 HL164424NIBIB NIH HHS R21 EB034579
6 · The paper itself

Abstract

Small, single-layer microfluidic paper-based analytical devices (µPADs) offer potential for a range of point-of-care applications; however, they have been limited to low flow rates. Here, we investigate the role of laser cutting paper channels in maximizing flow rate in small profile devices with limited fluid volumes. We demonstrate that branching, laser-cut grooves can provide a 59.23-73.98% improvement in flow rate over a single cut, and a 435% increase over paper alone. These design considerations can be applied to more complex microfluidic devices with the aim of increasing the flow rate, and could be used in stand-alone channels for self-pumping. Supplementary Information: The online version contains supplementary material available at 10.1007/s10404-023-02679-8.

Indexed as

Flow rateLow volumePaper microfluidicsPoint-of-care

Identifiers

PMID37719231
PMCPMC10499984

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.