Evidence map›Paper›PMID 37719061›Full record

ArticleThe Pan African medical journal2023

Left ventricular hypertrophy in African children infected with HIV/AIDS: a case-control study.

Ijeoma Ogugua Arodiwe, Christopher Bismarck Eke, Ejikeme Benneth Arodiwe

Abstract read
In one paragraph

Article in The Pan African medical journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Ijeoma Ogugua ArodiweDepartment of Paediatrics, College of Medicine, University of Nigeria Enugu Campus, Enugu, Nigeria.
Christopher Bismarck EkeDepartment of Paediatrics, College of Medicine, University of Nigeria Enugu Campus, Enugu, Nigeria.
Ejikeme Benneth ArodiweDepartment of Medicine, College of Medicine, University of Nigeria Enugu Campus, Enugu, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: left ventricular hypertrophy (LVH) measured by echocardiography seen in human immunodeficiency virus/acquired immunodeficiency disease (HIV/AIDS) affects the morbidity and mortality. The hemodynamic and metabolic changes in (HIV/AIDS) affect the heart adversely causing hypertrophic remodeling with left ventricular hypertrophy. The aim of this study was to determine the prevalence and risk factors associated with LVH in African children with HIV/AIDS. Methods: an analytical case-control study was conducted using echocardiography to assess cardiac function. Descriptive statistics was used to determine percentages and univariate analysis to find association between dependent variable and independent variables. Independent variables that had an association in a univariate were included in the multivariate model to determine strength of association. Results: the mean age of the study population was 7.8 ± 2.07 years for controls and 8.3 ± 3.04 years for cases respectively. They were made up of 51.2% (n= 86) males and 48.8% (n = 82) females (M: F=1.05: 1). We studied eighty-four (n= 84) cases, and LVH was seen in 67.7% (n= 56) of the patients. Mean left ventricular mass index (g/m Conclusion: the prevalence of LVH was high. Lower body mass index (BMI) and CD4+cells count predicted LVH. This supports the recommendation by the National Heart, Lung and Blood Institute (NHLBI) working group on research priorities for cardiovascular complications in HIV/AIDS, for baseline and periodic echocardiography in the management of children with HIV/AIDS.

Indexed as

HIV InfectionsHypertrophy, Left VentricularAfricaBlack PeopleCase-Control StudiesChildChild, PreschoolEchocardiographyFemaleHeartHumansInfantMalePrevalenceRisk FactorschildrenechocardiographyhypertrophyLeft ventricularretroviral infection

Identifiers

PMID37719061
PMCPMC10504446

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