Evidence map›Paper›PMID 37718762›Full record

SynthesisCell journal2023

Potential Utilisation of Secretome from Ascorbic Acid-Supplemented Stem Cells in Combating Skin Aging: Systematic Review of A Novel Idea.

Komang Ardi Wahyuningsih, Wimpie I Pangkahila, I Wayan Weta Weta, I Gde Raka Widiana, Ida Ayu Ika Wahyuniari

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in Cell journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Research Progress on Bioactive Factors against Skin Aging.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Komang Ardi WahyuningsihDoctoral Program, Faculty of Medicine, Universitas Udayana, Denpasar, Indonesia. Email: komang.wahyuningsih@atmajaya.ac.id.ORCID 0000-0002-5549-6571
Wimpie I PangkahilaDoctoral Program, Faculty of Medicine, Universitas Udayana, Denpasar, Indonesia.ORCID 0000-0002-1623-5395
I Wayan Weta WetaDoctoral Program, Faculty of Medicine, Universitas Udayana, Denpasar, Indonesia.ORCID 0000-0002-2447-1793
I Gde Raka WidianaDoctoral Program, Faculty of Medicine, Universitas Udayana, Denpasar, Indonesia.ORCID 0000-0002-2746-0192
Ida Ayu Ika WahyuniariDoctoral Program, Faculty of Medicine, Universitas Udayana, Denpasar, Indonesia.ORCID 0000-0003-3141-6247
Udayana University · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The secretome of stem cells consists of a spectrum of bioactive factors secreted by stem cells grown in culture mediacytokines, chemokines, and growth factors in addition to extracellular vesicles (exosomes and microvesicles). Ease of handling and storage of secretomes along with their bioactivity towards processes in skin aging and customizability makes them an appealing prospective therapy for skin aging. This systematic review aims to investigate the potential usage of ascorbic acid (AA)-supplemented stem cell secretomes (SCS) in managing skin aging. We extracted articles from three databases: PubMed, Scopus, and Cochrane. This review includes

Indexed as

Ascorbic AcidSecretomeSkin AgingStem Cells

Identifiers

PMID37718762
PMCPMC10520989
OpenAlexW4386817512

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.