Evidence map›Paper›PMID 37718394›Full record

ArticleZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics

[Comparison of the impact of different fat emulsions on clinical outcomes in preterm infants with varying duration of parenteral nutrition: a randomized controlled multicenter study].

Rong Lin, Qing Yang, Ya-Sen Wang, Wei Shen, Xin-Zhu Lin, Si-Yu Song, Juan Kong, Fan Wu, Dong Yang, Rui-Miao Bai and 7 more

Abstract readEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Article in Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. [Expert consensus on parenteral nutrition management in neonates (2025)].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Rong LinDepartment of Neonatology, Women and Children's Hospital, Xiamen University/Xiamen Maternal and Child Health Hospital/Xiamen Key Laboratory of Perinatal Neonatal Infection/Xiamen Clinical Research Center for Perinatal Medicine, Xiamen, Fujian 361003.
Qing YangDepartment of Neonatology, Women and Children's Hospital, Xiamen University/Xiamen Maternal and Child Health Hospital/Xiamen Key Laboratory of Perinatal Neonatal Infection/Xiamen Clinical Research Center for Perinatal Medicine, Xiamen, Fujian 361003.
Ya-Sen WangDepartment of Neonatology, Women and Children's Hospital, Xiamen University/Xiamen Maternal and Child Health Hospital/Xiamen Key Laboratory of Perinatal Neonatal Infection/Xiamen Clinical Research Center for Perinatal Medicine, Xiamen, Fujian 361003.
Wei ShenDepartment of Neonatology, Women and Children's Hospital, Xiamen University/Xiamen Maternal and Child Health Hospital/Xiamen Key Laboratory of Perinatal Neonatal Infection/Xiamen Clinical Research Center for Perinatal Medicine, Xiamen, Fujian 361003.
Xin-Zhu LinDepartment of Neonatology, Women and Children's Hospital, Xiamen University/Xiamen Maternal and Child Health Hospital/Xiamen Key Laboratory of Perinatal Neonatal Infection/Xiamen Clinical Research Center for Perinatal Medicine, Xiamen, Fujian 361003.
Si-Yu SongDepartment of Neonatology, Third Affiliated Hospital of Guangzhou Medical University, Guangzhou 510150, China.
Juan KongDepartment of Neonatology, Third Affiliated Hospital of Guangzhou Medical University, Guangzhou 510150, China.
Fan WuDepartment of Neonatology, Third Affiliated Hospital of Guangzhou Medical University, Guangzhou 510150, China.
Dong Yang
Rui-Miao Bai
Zhan-Kui Li
Shi-Rong Song
Wen-Ting Yu
Jian Mao
Yi-Jia Zhang
Juan Zhang
Xiao-Mei Tong

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo compare the impact of two types of fat emulsion on clinical outcomes in preterm infants with varying duration of parenteral nutrition (PN).

methodsPreterm infants meeting the inclusion criteria were randomly assigned to two groups: medium/long-chain triglyceride fat emulsion (referred to as MCT/LCT) group or multi-oil fat emulsion (containing soybean oil, medium-chain triglycerides, olive oil, and fish oil; referred to as SMOF) group. The infants were stratified into groups based on the duration of PN (15-21 days, 22-28 days, and ≥29 days). Clinical characteristics, nutritional status, biochemical indicators, and clinical outcomes were compared between the two groups.

resultsCompared with the MCT/LCT group, the SMOF group had lower peak levels of triglyceride during the hospital stay in preterm infants with PN of 15-21 days, 22-28 days, and ≥29 days, respectively (

conclusionsCompared to MCT/LCT, SMOF have better lipid tolerance. With a longer duration of PN, SMOF does not increase the risks of PNAC and BPD and had a protective effect against brain injury. This suggests that in preterm infants requiring long-term PN, the use of SMOF is superior to MCT/LCT.

Indexed as

Fat emulsionNutritionParenteral nutrition-associated cholestasisPreterm infantRandomized controlled trial

Identifiers

PMID37718394
PMCPMC10511226

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.