ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2024
Do stroke services still show sex differences? A multicenter study.
Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 11 citations in OpenAlex.
- Left Atrial Appendage: Mere Spectator or Protagonist? A Narrative Review of Its Multimodal Imaging Assessment and Its Closure Techniques.Journal of clinical medicine · 2026Review
- Post-stroke facial palsy: Prevalence, recovery patterns within the first 7 days, risk factors, and effect of hyperacute treatments.Clinical rehabilitation · 2026Article
- The interactive effect of sex and neutrophil-to-lymphocyte ratio on short-term poor outcomes in patients with nonvalvular atrial fibrillation-related acute cardioembolic stroke.European journal of medical research · 2025Article
- Quality of care for acute ischemic stroke in China during the COVID-19 pandemic: a retrospective study using a National database.BMC public health · 2025Observational
- Burden of stroke in adolescents and young adults (aged 15-39 years) in South East Asia: a trend analysis from 1990 to 2021 based on the global burden of disease study 2021.Frontiers in stroke · 2025Article
- Differences in characteristics between patients from Egypt and Germany presenting with lacunar stroke.Scientific reports · 2023Article
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Authors and funding
27 authors at 11 institutions in 10 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe issue of sex differences in stroke has gained concern in the past few years. However, multicenter studies are still required in this field. This study explores sex variation in a large number of patients and compares stroke characteristics among women in different age groups and across different countries.
methodsThis multicenter retrospective cross-sectional study aimed to compare sexes regarding risk factors, stroke severity, quality of services, and stroke outcome. Moreover, conventional risk factors in women according to age groups and among different countries were studied.
resultsEighteen thousand six hundred fifty-nine patients from 9 countries spanning 4 continents were studied. The number of women was significantly lower than men, with older age, more prevalence of AF, hypertension, and dyslipidemia. Ischemic stroke was more severe in women, with worse outcomes among women (p: < 0.0001), although the time to treatment was shorter. Bridging that was more frequent in women (p:0.002). Analyzing only women: ischemic stroke was more frequent among the older, while hemorrhage and TIA prevailed in the younger and stroke of undetermined etiology. Comparison between countries showed differences in age, risk factors, type of stroke, and management.
conclusionWe observed sex differences in risk factors, stroke severity, and outcome in our population. However, access to revascularization was in favor of women.
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