Evidence map›Paper›PMID 37717020›Full record

ArticleJournal of nanobiotechnology2023

Targeted co-delivery of curcumin and erlotinib by MoS

Zhihuai Chen, Xinqi Wei, Yunru Zheng, Zongwei Zhang, Wang Gu, Wenjun Liao, Hua Zhang, Xiaoying Wang, Jian Liu, Hua Li and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of nanobiotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Engineered MoSNanomaterials (Basel, Switzerland) · 2026
    Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Zhihuai Chen *Institute of Structural Pharmacology & TCM Chemical Biology, College of Pharmacy, Fujian University of Traditional Chinese Medicine, No. 1, Qiuyang Road, Fuzhou, 350122, Fujian, China.
Xinqi Wei *Institute of Structural Pharmacology & TCM Chemical Biology, College of Pharmacy, Fujian University of Traditional Chinese Medicine, No. 1, Qiuyang Road, Fuzhou, 350122, Fujian, China.
Yunru ZhengInstitute of Structural Pharmacology & TCM Chemical Biology, College of Pharmacy, Fujian University of Traditional Chinese Medicine, No. 1, Qiuyang Road, Fuzhou, 350122, Fujian, China.
Zongwei ZhangInstitute of Structural Pharmacology & TCM Chemical Biology, College of Pharmacy, Fujian University of Traditional Chinese Medicine, No. 1, Qiuyang Road, Fuzhou, 350122, Fujian, China.
Wang GuInstitute of Structural Pharmacology & TCM Chemical Biology, College of Pharmacy, Fujian University of Traditional Chinese Medicine, No. 1, Qiuyang Road, Fuzhou, 350122, Fujian, China.
Wenjun LiaoKey Laboratory of Gastrointestinal Cancer, Ministry of Education, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, 350005, China.
Hua ZhangInstitute of Structural Pharmacology & TCM Chemical Biology, College of Pharmacy, Fujian University of Traditional Chinese Medicine, No. 1, Qiuyang Road, Fuzhou, 350122, Fujian, China.
Xiaoying WangInstitute of Structural Pharmacology & TCM Chemical Biology, College of Pharmacy, Fujian University of Traditional Chinese Medicine, No. 1, Qiuyang Road, Fuzhou, 350122, Fujian, China.
Jian LiuInstitute of Structural Pharmacology & TCM Chemical Biology, College of Pharmacy, Fujian University of Traditional Chinese Medicine, No. 1, Qiuyang Road, Fuzhou, 350122, Fujian, China. 2020026@fjtcm.edu.cn.
Hua LiInstitute of Structural Pharmacology & TCM Chemical Biology, College of Pharmacy, Fujian University of Traditional Chinese Medicine, No. 1, Qiuyang Road, Fuzhou, 350122, Fujian, China. 2022041@fjtcm.edu.cn.
Wei XuInstitute of Structural Pharmacology & TCM Chemical Biology, College of Pharmacy, Fujian University of Traditional Chinese Medicine, No. 1, Qiuyang Road, Fuzhou, 350122, Fujian, China. 2000017@fjtcm.edu.cn.
Fujian University of Traditional Chinese Medicine · CNFujian Medical University · CN

Funding

the Fujian University of Traditional Chinese Medicine Foundation 701200001the Fujian University of Traditional Chinese Medicine Foundation X2019004the National Natural Science of China 82104406the Natural Science Foundation of Fujian Province 2021J01922
6 · The paper itself

Abstract

backgroundCurcumin (Cur), a bioactive component of Chinese traditional medicine, has demonstrated inhibitory properties against cancer cell proliferation while synergistically enhancing the anticancer efficacy of erlotinib (Er). However, the individual limitations of both drugs, including poor aqueous solubility, lack of targeting ability, short half-life, etc., and their distinct pharmacokinetic profiles mitigate or eliminate their combined antitumor potential.

resultsIn this study, we developed a molybdenum disulfide (MoS

conclusionsThe as-synthesized MoS

Indexed as

CurcuminLung NeoplasmsBiotinErlotinib HydrochlorideHumansMolybdenumPhotothermal TherapyPolyethylene GlycolsBiotinCurcuminErlotinib HydrochlorideMolybdenumPolyethylene GlycolsBiotinMoS2 nanosheetsNIR light-responsive drug releasePhotothermal therapySynergistic chemotherapy

Identifiers

PMID37717020
PMCPMC10505307
OpenAlexW4386802359

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.