Evidence map›Paper›PMID 37716970›Full record

Trial reportMalaria journal2023

Evaluating the attrition, fabric integrity and insecticidal durability of two dual active ingredient nets (Interceptor

Corine Ngufor, Augustin Fongnikin, Josias Fagbohoun, Abel Agbevo, Thomas Syme, Juniace Ahoga, Manfred Accrombessi, Natacha Protopopoff, Jackie Cook, Thomas S Churcher and 3 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Malaria journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

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  10. Functional Validation of Endogenous Redox PartnerInternational journal of molecular sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Corine NguforLondon School of Hygiene and Tropical Medicine (LSHTM), London, WC1E 7HT, UK. corine.ngufor@lshtm.ac.uk.
Augustin FongnikinCentre de Recherches Entomologiques de Cotonou (CREC), Cotonou, Benin.
Josias FagbohounCentre de Recherches Entomologiques de Cotonou (CREC), Cotonou, Benin.
Abel AgbevoLondon School of Hygiene and Tropical Medicine (LSHTM), London, WC1E 7HT, UK.
Thomas SymeLondon School of Hygiene and Tropical Medicine (LSHTM), London, WC1E 7HT, UK.
Juniace AhogaCentre de Recherches Entomologiques de Cotonou (CREC), Cotonou, Benin.
Manfred AccrombessiLondon School of Hygiene and Tropical Medicine (LSHTM), London, WC1E 7HT, UK.
Natacha ProtopopoffLondon School of Hygiene and Tropical Medicine (LSHTM), London, WC1E 7HT, UK.
Jackie CookLondon School of Hygiene and Tropical Medicine (LSHTM), London, WC1E 7HT, UK.
Thomas S ChurcherMRC Centre for Global Infectious Disease Analysis, Infectious Disease Epidemiology, Imperial College London, Norfolk Place, London, W2 1PG, UK.
Germain Gil PadonouCentre de Recherches Entomologiques de Cotonou (CREC), Cotonou, Benin.
Renaud GovoetchanLondon School of Hygiene and Tropical Medicine (LSHTM), London, WC1E 7HT, UK.
Martin AkogbetoCentre de Recherches Entomologiques de Cotonou (CREC), Cotonou, Benin.
London School of Hygiene & Tropical Medicine · GBImperial College London · GB

Funding

Medical Research Council MR/R010161/1
6 · The paper itself

Abstract

backgroundFollowing the World Health Organization (WHO) endorsement of dual active ingredient (AI) nets, an increased uptake of pyrethroid-chlorfenapyr and pyrethroid-pyriproxyfen nets is expected. Studies evaluating their physical and insecticidal durability are essential for making programmatic and procurement decisions. This paper describes the methodology for a prospective study to evaluate the attrition, fabric integrity, insecticidal durability of Interceptor

methodsTen clusters randomly selected from each arm of the cRCT will be used for the study. A total of 750 ITNs per type will be followed in 5 study clusters per arm to assess ITN attrition and fabric integrity at 6-, 12-, 24- and 36-months post distribution, using standard WHO procedures. A second cohort of 1800 nets per type will be withdrawn every 6 months from all 10 clusters per arm and assessed for chemical content and biological activity in laboratory bioassays at each time point. Alpha-cypermethrin bioefficacy in Interceptor

conclusionThis study will provide information on the durability of two dual AI nets (Interceptor

Indexed as

AnophelesInsecticidesAnimalsBeninHumansMacrolidesProspective StudiesPyrethrinschlorfenapyrcypermethrinInsecticidesMacrolidesmilbemycin oximePyrethrinsAlpha-cypermethrinAttritionBioefficacyChlorfenapyrDual active ingredient netsDurabilityExperimental hut trialsFabric integrityInsecticide Treated NetInterceptor®Interceptor® G2PyriproxyfenRoyal Guard®

Identifiers

PMID37716970
PMCPMC10504698
OpenAlexW4386798998

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.