SynthesisBMC oral health2023
Oral health-related quality of life in patients aged 8 to 19 years with cleft lip and palate: a systematic review and meta-analysis.
Synthesis in BMC oral health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 17 citations in OpenAlex.
- The Impact of Child Life Intervention on Psychological Status and Quality of Life in Children With Cleft Lip and Palate.The Journal of craniofacial surgery · 2026Article
- Positive Longitudinal Caregiver Behavioral Ratings and Self-Reported Quality of Life in Youth With Cleft Lip and Palate in Treatment for Class III Malocclusion.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2026Article
- Prevalence of orofacial cleft and its associated factors among newborns in Kembata zone, central Ethiopia 2024.BMC oral health · 2026Article
- Oral health-related quality of life in adults with cleft lip and/or palate: A systematic review.Dental research journal · 2026Review
- Treatment perspectives and concerns among pediatric cleft lip and palate patients: a cross-sectional study.BMC oral health · 2025Article
- Treatment Outcomes of Cleft Lip and Cleft Palate Healthcare Network in Northern Thailand.Plastic and reconstructive surgery. Global open · 2025Article
- Nasolabial shape and aesthetics in patients with cleft lip and palate: analysis of 3D facial images.European journal of orthodontics · 2025Article
- Oral Health-Related Quality of Life After Allogeneic Bone Marrow Transplant-A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2025Article
- Oral health-related quality of life and dental occlusion before and after alveolar and hard palate reconstruction at the time of mixed dentition.Frontiers in oral health · 2025Article
- Evaluating quality of life changes in patients with cleft lip or palate: a mixed method pre- and postsurgical analysis in Karachi.BMC oral health · 2024Article
- Prevalence of tooth agenesis and supernumerary teeth related to different Thai cleft lip and cleft palate populations.BMC oral health · 2024Article
- The Global Occurrences of Cleft Lip and Palate in Pediatric Patients and Their Association with Demographic Factors: A Narrative Review.Children (Basel, Switzerland) · 2024Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCleft lip and palate (CLP) is the most common facial birth defect worldwide and causes morphological, aesthetic, and functional problems with psychosocial implications for an individual's life and well-being. The present systematic review and meta-analysis assessed whether the treatment of CLP impacts the oral health-related quality of life (OHRQoL) in children and adolescents in comparison to healthy controls.
methodsWe searched MEDLINE/PubMed, EMBASE, and PsycINFO databases using terms related to CLP, and included articles until August 2023. Observational comparison studies that assessed OHRQoL in non-syndromic CLP patients aged 8-19 years with validated scales designed to such aim or scales capable to identify aspects related to oral health compared to healthy controls were included. We used the ROBINS-I tool for risk of bias assessment. A meta-analysis of continuous variables was performed using inverse variance for pooling estimates, Standardized Mean Difference (SMD) as a summary measure, with random effects model. Heterogeneity was estimated by the I
resultsFourteen studies were included comprising 1,185 patients with CLP and 1,558 healthy controls. The direction of the effect of OHRQoL favoured the healthy group (-0.92; 95% CI:-1,55;-0,10) and I
conclusionThe global OHRQoL is slightly worst in the CLP patients than control group. The difference between OHRQoL was mainly detected through OHIP. The most affected domains are functional, emotional and social. SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42022336956.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.