Evidence map›Paper›PMID 37716829›Full record

ArticleVaccine2023

Evaluation of an iELISA for detection and quantification of rabies antibodies in domestic dog sera.

Ahmed Lugelo, Katie Hampson, Lorraine M McElhinney, Felix Lankester

Open access · hybridAbstract read
In one paragraph

Article in Vaccine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Ahmed LugeloGlobal Animal Health Tanzania, Arusha, Tanzania; Boyd Orr Centre for Population and Ecosystem Health, School of Biodiversity, One Health and Veterinary Medicine, University of Glasgow, Glasgow G12 8QQ, UK. Electronic address: ahmed.lugelo@wsu.edu.
Katie HampsonBoyd Orr Centre for Population and Ecosystem Health, School of Biodiversity, One Health and Veterinary Medicine, University of Glasgow, Glasgow G12 8QQ, UK.
Lorraine M McElhinneyViral Zoonoses Group, Animal and Plant Health Agency (APHA), Weybridge, New Haw, Addlestone, Surrey KT15 3NB, UK.
Felix LankesterGlobal Animal Health Tanzania, Arusha, Tanzania; Boyd Orr Centre for Population and Ecosystem Health, School of Biodiversity, One Health and Veterinary Medicine, University of Glasgow, Glasgow G12 8QQ, UK; Paul G. Allen School for Global Animal Health, Washington State University, Pullman, WA 99164, USA. Electronic address: felix.lankester@wsu.edu.
Glasgow Centre for Population Health · GBAnimal and Plant Health Agency · GB

Funding

Eliminating human rabies: impact of enhanced vaccination coverageR01AI141712 · NIAID · WASHINGTON STATE UNIVERSITY · PI LANKESTER, FELIX · 2019 to 2023
$2.3M
NIAID NIH HHS R01 AI141712Wellcome Trust 207569/Z/17/Z
6 · The paper itself

Abstract

Many rabies endemic-countries have recognized rabies as a public health problem that can be eliminated. As a result, some countries have started implementing small-scale vaccination programs with the aim of scaling them up. Post-vaccination serological monitoring is crucial to assess the efficacy of these programs. The recommended serological tests, the rapid fluorescent focus inhibition test, and the fluorescent antibody virus neutralization (FAVN) are accurate; however, the procedures require considerable expertise and must be carried out in high containment facilities, which are often not available in rabies endemic countries. Given these constraints, enzyme linked immunosorbent assays (ELISAs) have been considered as alternative methods to neutralization tests. This is the first study to evaluate, under field conditions, the performance of the commercial rabies indirect-ELISA (iELISA), the Platelia

Indexed as

Dog DiseasesRabiesRabies VaccinesRabies virusAnimalsAntibodies, ViralDogsEnzyme-Linked Immunosorbent AssayImmunologic FactorsSensitivity and SpecificityVaccinationAntibodies, ViralImmunologic FactorsRabies VaccinesCanine rabiesFAVNiELISAMass dog vaccinationPlatelia(TM) Rabies IIRabies serology

Identifiers

PMID37716829
PMCPMC11717753
OpenAlexW4386759962

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.