Evidence map›Paper›PMID 37716611›Full record

Trial reportThe Journal of nutrition2023

Algae Ingestion Increases Resting and Exercised Myofibrillar Protein Synthesis Rates to a Similar Extent as Mycoprotein in Young Adults.

Ino van der Heijden, Sam West, Alistair J Monteyne, Tim J A Finnigan, Doaa R Abdelrahman, Andrew J Murton, Francis B Stephens, Benjamin T Wall

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The Journal of nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Ingestion of 'whole cell' or 'split cell'Frontiers in nutrition · 2024
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Ino van der HeijdenDepartment of Public Health and Sport Sciences, Faculty of Health and Life Sciences, University of Exeter, Exeter, United Kingdom.
Sam WestDepartment of Public Health and Sport Sciences, Faculty of Health and Life Sciences, University of Exeter, Exeter, United Kingdom.
Alistair J MonteyneDepartment of Public Health and Sport Sciences, Faculty of Health and Life Sciences, University of Exeter, Exeter, United Kingdom.
Tim J A FinniganNew Era Foods, Yarm, United Kingdom.
Doaa R AbdelrahmanDepartment of Surgery, University of Texas Medical Branch, Galveston, TX, United States; Sealy Center on Aging, University of Texas Medical Branch, Galveston, TX, United States.
Andrew J MurtonDepartment of Surgery, University of Texas Medical Branch, Galveston, TX, United States; Sealy Center on Aging, University of Texas Medical Branch, Galveston, TX, United States.
Francis B StephensDepartment of Public Health and Sport Sciences, Faculty of Health and Life Sciences, University of Exeter, Exeter, United Kingdom.
Benjamin T WallDepartment of Public Health and Sport Sciences, Faculty of Health and Life Sciences, University of Exeter, Exeter, United Kingdom. Electronic address: b.t.wall@exeter.ac.uk.
University of Exeter · GBThe University of Texas Medical Branch at Galveston · USQuorn (United Kingdom) · GB

Funding

UTMB OAIC Research Education Component (REC)P30AG024832 · NIA · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI JAMES S. GOODWIN, MD, MELISSA M. MORROW · 2005 to 2026
$26.7M
6 · The paper itself

Abstract

backgroundSpirulina [SPIR] (cyanobacterium) and chlorella [CHLO] (microalgae) are foods rich in protein and essential amino acids; however, their capacity to stimulate myofibrillar protein synthesis (MyoPS) in humans remains unknown.

objectivesWe assessed the impact of ingesting SPIR and CHLO compared with an established high-quality nonanimal-derived dietary protein source (fungal-derived mycoprotein [MYCO]) on plasma amino acid concentrations, as well as resting and postexercise MyoPS rates in young adults.

methodsThirty-six healthy young adults (age: 22 ± 3 y; BMI: 23 ± 3 kg·m

resultsProtein ingestion increased the plasma total and essential amino acid concentrations (time effects; all P < 0.001), but most rapidly and with higher peak responses following the ingestion of SPIR compared with MYCO and CHLO (P < 0.05), and MYCO compared with CHLO (P < 0.05). Protein ingestion increased MyoPS rates (time effect; P < 0.001) in both rested (MYCO, from 0.041 ± 0.032 to 0.060 ± 0.015%·h

conclusionsThe ingestion of a single bolus of algae-derived SPIR and CHLO increases resting and postexercise MyoPS rates to a comparable extent as MYCO, despite divergent postprandial plasma amino acid responses.

Indexed as

ChlorellaResistance TrainingAdultAmino Acids, EssentialDietary ProteinsEatingFemaleHumansMaleMuscle ProteinsMuscle, SkeletalPhenylalanineYoung AdultAmino Acids, EssentialDietary ProteinsMuscle ProteinsPhenylalaninealgaeamino acidsmuscle protein synthesismycoproteinresistance exercisestable isotopes

Identifiers

PMID37716611
PMCPMC10739781
OpenAlexW4386790119

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.