Evidence map›Paper›PMID 37716019›Full record

ArticleBehaviour research and therapy2023

Guided LGBTQ-affirmative internet cognitive-behavioral therapy for sexual minority youth's mental health: A randomized controlled trial of a minority stress treatment approach.

John E Pachankis, Zachary A Soulliard, Eric K Layland, Kriti Behari, Ilana Seager van Dyk, Benjamin E Eisenstadt, Danielle Chiaramonte, Brjánn Ljótsson, Josefin Särnholm, Johan Bjureberg

Abstract read
In one paragraph

Article in Behaviour research and therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

John E PachankisYale School of Public Health, USA. Electronic address: john.pachankis@yale.edu.
Zachary A SoulliardYale School of Public Health, USA.
Eric K LaylandYale School of Public Health, USA.
Kriti BehariYale School of Public Health, USA.
Ilana Seager van DykYale School of Public Health, USA.
Benjamin E EisenstadtYale School of Public Health, USA.
Danielle ChiaramonteYale School of Public Health, USA.
Brjánn LjótssonDivision for Psychology, Department of Clinical Neuroscience, Karolinska Institutet, Sweden.
Josefin SärnholmDivision for Psychology, Department of Clinical Neuroscience, Karolinska Institutet, Sweden.
Johan BjurebergCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, & Stockholm Health Care Services, Region Stockholm, Sweden.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
INTERDISCIPLINARY HIV PREVENTION TRAINING PROGRAMT32MH020031 · NIMH · YALE UNIVERSITY · PI Trace S Kershaw · 1999 to 2026
$12.1M
A unified intervention for young gay and bisexual men's minority stress, mental health, and HIV riskR01MH109413 · NIMH · YALE UNIVERSITY · PI PACHANKIS, JOHN EDWARD · 2016 to 2020
$4.5M
NCATS NIH HHS UL1 TR001863NIMH NIH HHS R01 MH109413NIMH NIH HHS T32 MH020031
6 · The paper itself

Abstract

objectiveLGBTQ-affirmative cognitive-behavioral therapy (CBT) addresses the adverse impacts of minority stress. However, this treatment has rarely been tested in randomized controlled trials with LGBTQ youth and never using an asynchronous online platform for broad reach. This study examined the feasibility, acceptability, preliminary efficacy, and multi-level stigma moderators of LGBTQ-affirmative internet-based CBT (ICBT).

methodParticipants were 120 LGBTQ youth (ages 16-25; 37.5% transgender or non-binary; 75.8% assigned female at birth; 49.2% non-Latino White) living across 38 U.S. states and reporting depression and/or anxiety symptoms. Participants were randomized to receive 10 sessions of LGBTQ-affirmative ICBT or only complete 10 weekly assessments of mental and behavioral health and minority stress; all completed measures of psychological distress, depression, anxiety, suicidal thoughts, alcohol use, and HIV-transmission-risk behavior at baseline and 4 and 8 months post-baseline; 20 LGBTQ-affirmative ICBT participants completed a qualitative interview regarding intervention acceptability.

resultsParticipants randomized to LGBTQ-affirmative ICBT completed, on average, 6.08 (SD = 3.80) sessions. Participants reported that LGBTQ-affirmative ICBT was helpful and engaging and provided suggestions for enhancing engagement. Although most outcomes decreased over time, between-group comparisons were small and non-significant. LGBTQ-affirmative ICBT was more efficacious in reducing psychological distress than assessment-only for participants in counties high in anti-LGBTQ bias (b = -1.73, p = 0.001, 95% CI [-2.75, -0.70]). Session dosage also significantly predicted reduced depression and anxiety symptoms.

conclusionsLGBTQ-affirmative ICBT represents a feasible and acceptable treatment. Future research can identify more efficacious approaches and modalities for engaging LGBTQ youth, especially those living under stigmatizing conditions, who might benefit most.

Indexed as

Cognitive Behavioral TherapySexual and Gender MinoritiesAdolescentAdultAnxiety DisordersFemaleHumansInternetMaleMental HealthRandomized Controlled Trials as TopicYoung AdultDepressionEvidence-based practiceMinority stressSexual and gender minorityStigma

Identifiers

PMID37716019
PMCPMC10601985

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.