ArticleApplied biochemistry and biotechnology2024
Development of Green-Synthesized Carbon-Based Nanoparticle for Prevention of Surface Wound Biofilm.
Article in Applied biochemistry and biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The development of microbial biofilm occurs with the adherence of the microbial cells on biotic and abiotic surfaces with the help of pili and with extracellular polymeric substances. The surfaces on which biofilm formation take place can be inert, abiotic, or biotic. The sessile microbial cells behave differently from their planktonic counterpart. The biofilm developed by Alcaligenes faecalis is responsible for the development of skin and soft-tissue infection. It was observed that green-synthesized carbon nanoparticles (NPs) from Ocimum sanctum showed a prolonged stability and activity. It showed a marked reduction in the viability of sessile microbial species with least revival in comparison to the plant extract and amoxicillin. It was observed that carbon NP was able to maximally reduce the quorum sensing (QS) activity of A. faecalis. Thus, the use of green-synthesized NPs would be an alternative in the treatment of the biofilm-associated chronic wound infections.
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