Evidence map›Paper›PMID 37715739›Full record

ReviewPathogens and global health2024

Human mpox: global trends, molecular epidemiology and options for vaccination.

Lorenzo Subissi, Paola Stefanelli, Giovanni Rezza

Open access · greenAbstract readReview
In one paragraph

Review in Pathogens and global health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Lorenzo SubissiHealth Emergencies Programme, World Health Organization, Geneva, Switzerland.
Paola StefanelliDepartment of Infectious Diseases, Istituto Superiore di Sanità, Roma, Italy.
Giovanni RezzaHealth Prevention Directorate, Ministry of Health, Roma, Italy.
Istituto Superiore di Sanità · ITMinistero della Salute · ITWorld Health Organization · CH

Funding

World Health Organization 001
6 · The paper itself

Abstract

The eradication of smallpox and the cessation of vaccination have led to the growth of the susceptible human population to poxviruses. This has led to the increasing detection of zoonotic orthopoxviruses. Among those viruses, monkeypox virus (MPV) is the most commonly detected in Western and Central African regions. Since 2022, MPV is causing local transmission in newly affected countries all over the world. While the virus causing the current outbreak remains part of clade II (historically referred to as West African clade), it has a significant number of mutations as compared to other clade II sequences and is therefore referred to as clade IIb. It remains unclear whether those mutations may have caused a change in the virus phenotype. Vaccine effectiveness data show evidence of a high cross-protection of vaccines designed to prevent smallpox against mpox. These vaccines therefore represent a great opportunity to control human-to-human transmission, provided that their availability has short time-frames and that mistakes from the recent past (vaccine inequity) will not be reiterated.

Indexed as

Mpox, MonkeypoxSmallpoxVaccinesHumansMolecular EpidemiologyMonkeypox virusVaccinationVaccinesmolecular epidemiologymonkeypoxMpoxorthopoxvirussmallpox vaccination

Identifiers

PMID37715739
PMCPMC10769137
OpenAlexW4386801350

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.