Evidence map›Paper›PMID 37715703›Full record

ArticleThe Journal of physiology2023

Age-related changes in P2Y receptor signalling in mouse cochlear supporting cells.

Sarah A Hool, Jing-Yi Jeng, Daniel J Jagger, Walter Marcotti, Federico Ceriani

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in The Journal of physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Spontaneous Calcium Signalling in the Developing Mammalian Cochlea.Journal of the Association for Research in Otolaryngology : JARO · 2026
    Review
  2. Article
  3. Spontaneous CaExperimental physiology · 2026
    Article
  4. In vivo spontaneous CaNature communications · 2025
    Article
  5. Review
  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Sarah A HoolSchool of Biosciences, University of Sheffield, Sheffield, UK.ORCID 0009-0000-9896-4534
Jing-Yi JengSchool of Biosciences, University of Sheffield, Sheffield, UK.ORCID 0000-0002-6274-8597
Daniel J JaggerUCL Ear Institute, University College London, London, UK.ORCID 0000-0003-2796-5526
Walter MarcottiSchool of Biosciences, University of Sheffield, Sheffield, UK.ORCID 0000-0002-8770-7628
Federico CerianiSchool of Biosciences, University of Sheffield, Sheffield, UK.ORCID 0000-0002-5366-341X
University of Sheffield · GBUniversity College London · GB

Funding

Biotechnology and Biological Sciences Research Council BB/V006681/1
6 · The paper itself

Abstract

Our sense of hearing depends on the function of a specialised class of sensory cells, the hair cells, which are found in the organ of Corti of the mammalian cochlea. The unique physiological environment in which these cells operate is maintained by a syncitium of non-sensory supporting cells, which are crucial for regulating cochlear physiology and metabolic homeostasis. Despite their importance for cochlear function, the role of these supporting cells in age-related hearing loss, the most common sensory deficit in the elderly, is poorly understood. Here, we investigated the age-related changes in the expression and function of metabotropic purinergic receptors (P2Y

Indexed as

CalciumHearing LossAdenosine TriphosphateAgedAnimalsHumansInfantMammalsMiceMice, Inbred C3HMice, Inbred C57BLReceptors, PurinergicReceptors, Purinergic P2YReceptors, Purinergic P2Y1Receptors, Purinergic P2Y2Adenosine TriphosphateCalciumReceptors, PurinergicReceptors, Purinergic P2YReceptors, Purinergic P2Y1Receptors, Purinergic P2Y2ageingcalcium signallingcochleapurinergic receptorssupporting cells

Identifiers

PMID37715703
PMCPMC10952729
OpenAlexW4386802212

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.