Evidence map›Paper›PMID 37715370›Full record

ReviewInternational journal of cancer2024

State of the science and future directions for research on HIV and cancer: Summary of a joint workshop sponsored by IARC and NCI.

Eric A Engels, Meredith S Shiels, Ruanne V Barnabas, Julia Bohlius, Paul Brennan, Jessica Castilho, Stephen J Chanock, Megan A Clarke, Anna E Coghill, Jean-Damien Combes and 19 more

Open access · hybridAbstract readReview
In one paragraph

Review in International journal of cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 19 citations in OpenAlex.

  1. Trial
  2. Article
  3. Observational
  4. Incidence of dementia after a recent cancer diagnosis among people with HIV.medRxiv : the preprint server for health sciences · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Excess Mortality in Persons with Concurrent HIV and Cancer Diagnoses: A Retrospective Cohort Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors at 17 institutions in 6 countries.

Eric A EngelsDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland, USA.
Meredith S ShielsDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland, USA.ORCID 0000-0001-8390-6091
Ruanne V BarnabasDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.
Julia BohliusUniversity of Basel, Basel, Switzerland.
Paul BrennanGenomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France.
Jessica CastilhoDivision of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Stephen J ChanockDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland, USA.
Megan A ClarkeDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland, USA.ORCID 0000-0003-0435-7376
Anna E CoghillDepartment of Cancer Epidemiology and Center for Immunization and Infection Research in Cancer, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA.ORCID 0000-0001-7142-7499
Jean-Damien CombesInternational Agency for Research on Cancer (IARC/WHO), Early Detection, Prevention and Infections Branch, Lyon, France.
Scott Dryden-PetersonBrigham and Women's Hospital, Boston, Massachusetts, USA.
Gypsyamber D'SouzaDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Satish GopalCenter for Global Health, National Cancer Institute, National Institutes of Health, Rockville, Maryland, USA.
Antoine JaquetNational Institute for Health and Medical Research (INSERM), UMR, 1219, Research Institute for Sustainable Development (IRD), EMR 271, Bordeaux Population, Health Centre, University of Bordeaux, Bordeaux, France.ORCID 0000-0002-3426-9492
Kathryn LurainHIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
Alain MakinsonInfectious Disease Department, CHU La Colombière, Montpellier & Inserm U1175, University of Montpellier, Montpellier, France.
Jeffrey MartinDepartment of Epidemiology and Biostatistics, University of California, San Francisco, California, USA.
Mazvita MuchengetiNational Cancer Registry, National Health Laboratory Service, Johannesburg, South Africa.ORCID 0000-0002-1955-923X
Robert NewtonMRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.
Fred OkukuUganda Cancer Institute, Kampala, Uganda.
Jackson OremUganda Cancer Institute, Kampala, Uganda.
Joel M PalefskyDepartment of Medicine, University of California, San Francisco, California, USA.
Ramya RamaswamiHIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
Hilary A RobbinsGenomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France.
Keith SigelDivision of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Sylvia SilverGeorge Washington University, Washington, DC, USA.
Gita SunejaDepartment of Radiation Oncology, Huntsman Cancer Institute at the University of Utah, Salt Lake City, Utah, USA.
Robert YarchoanHIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
Gary M CliffordInternational Agency for Research on Cancer (IARC/WHO), Early Detection, Prevention and Infections Branch, Lyon, France.ORCID 0000-0001-7534-333X
National Institutes of Health · USCentre international de recherche sur le cancer · FRUganda Cancer Institute · UGUniversity of California, San Francisco · USBrigham and Women's Hospital · USGeorge Washington University · USIcahn School of Medicine at Mount Sinai · USInserm · FRJohns Hopkins University · USMassachusetts General Hospital · USMoffitt Cancer Center · USNational Health Laboratory Service · ZASwiss Tropical and Public Health Institute · CHUniversité de Bordeaux · FRUniversity of Utah · USUniversity of York · GBVanderbilt University Medical Center · US

Funding

Clinical Trials of Patients with AIDS-Related MalignanciesZIABC010888 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI YARCHOAN, ROBERT · 2009 to 2025
$20.6M
Study of Tumor Pathogenesis and Development of Therapies for AIDS MalignanciesZIABC010885 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI YARCHOAN, ROBERT · 2009 to 2025
$15.7M
United States-East Africa HIV-Associated Malignancy Research Center (USEAHAMRC) for Career Development and the Prevention, Early Detection and Efficient Linkage to Care for Virus-related CancersU54CA254571 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MARTIN, JEFFREY N · 2020 to 2025
$5.6M
Targeted therapies for Kaposi sarcoma and KSHV-multicentric Castleman diseaseZIABC011954 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI RAMASWAMI, RAMYA · 2020 to 2025
$3.8M
Covid-19-related cervical cancer treatment interruption and role of neoadjuvant chemotherapyR01CA236546 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI DRYDEN-PETERSON, SCOTT · 2019 to 2023
$2.5M
Botswana CASCADE Clinical Trials SiteUG1CA275416 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI Scott Dryden-Peterson, Doreen Ramogola-Masire · 2022 to 2026
$1.4M
Optimizing Screening for HPV-related Cancers among People Living with HIVF31CA210660 · NCI · JOHNS HOPKINS UNIVERSITY · PI ROBBINS, HILARY A. · 2016 to 2017
$82k
NCI NIH HHS F31 CA210660NCI NIH HHS R01 CA236546NCI NIH HHS U54 CA254571NCI NIH HHS UG1 CA275416World Health Organization 001
6 · The paper itself

Abstract

An estimated 38 million people live with human immunodeficiency virus (HIV) worldwide and are at excess risk for multiple cancer types. Elevated cancer risks in people living with HIV (PLWH) are driven primarily by increased exposure to carcinogens, most notably oncogenic viruses acquired through shared transmission routes, plus acceleration of viral carcinogenesis by HIV-related immunosuppression. In the era of widespread antiretroviral therapy (ART), life expectancy of PLWH has increased, with cancer now a leading cause of co-morbidity and death. Furthermore, the types of cancers occurring among PLWH are shifting over time and vary in their relative burden in different parts of the world. In this context, the International Agency for Research on Cancer (IARC) and the US National Cancer Institute (NCI) convened a meeting in September 2022 of multinational and multidisciplinary experts to focus on cancer in PLWH. This report summarizes the proceedings, including a review of the state of the science of cancer descriptive epidemiology, etiology, molecular tumor characterization, primary and secondary prevention, treatment disparities and survival in PLWH around the world. A consensus of key research priorities and recommendations in these domains is also presented.

Indexed as

Anti-HIV AgentsHIV InfectionsNeoplasmsHIVHumansNational Cancer Institute (U.S.)United StatesAnti-HIV Agentscancerepidemiologyhuman immunodeficiency viruspeople living with HIVprevention

Identifiers

PMID37715370
PMCPMC11133517
OpenAlexW4386796230

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.