Evidence map›Paper›PMID 37715369›Full record

Observational studyAddiction (Abingdon, England)2024

Identifying patients with opioid use disorder using International Classification of Diseases (ICD) codes: Challenges and opportunities.

Katie P Osterhage, Yih-Ing Hser, Larissa J Mooney, Seth Sherman, Andrew J Saxon, Maja Ledgerwood, Caleb C Holtzer, Margaret A Gehring, Sarah E Clingan, Megan E Curtis and 1 more

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in Addiction (Abingdon, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 22 citations in OpenAlex.

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  13. Use of Medications for Opioid Use Disorder in Older Adults.American journal of preventive medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Katie P OsterhageDepartment of Family Medicine, University of Washington, Seattle, Washington, USA.ORCID 0000-0001-9112-2262
Yih-Ing HserDepartment of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, California, USA.
Larissa J MooneyDepartment of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, California, USA.
Seth ShermanThe Emmes Company, Rockville, Maryland, USA.
Andrew J SaxonDepartment of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, Washington, USA.
Maja LedgerwoodRural Social Service Solutions, LLC, New Meadows, Idaho, USA.
Caleb C HoltzerProvidence Northeast Washington Medical Group, Colville, Washington, USA.
Margaret A GehringSt. Mary's Health, Cottonwood, Idaho, USA.
Sarah E ClinganDepartment of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, California, USA.ORCID 0000-0002-2714-2039
Megan E CurtisDepartment of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, California, USA.
Laura-Mae BaldwinDepartment of Family Medicine, University of Washington, Seattle, Washington, USA.
University of California, Los Angeles · USUniversity of Washington · USEmmes (United States) · USProvidence Regional Medical Center Everett · USSt. Mary's Medical Center · USUniversity of Idaho · US

Funding

Clinical Trials Network: Pacific Northwest Node (CTN-0082, -0131, -0139 and dissemination library)UG1DA013714 · NIDA · UNIVERSITY OF WASHINGTON · PI Mary Akiko Hatch, John M. Roll · 2015 to 2026
$19.8M
Greater Southern California Node of the Clinical Trials NetworkUG1DA049435 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI YIH-ING HSER · 2019 to 2026
$16.7M
NIDA NIH HHS UG1 DA013714NIDA NIH HHS UG1 DA049435
6 · The paper itself

Abstract

BACKGROUND AND

aimsInternational Classification of Diseases (ICD) diagnosis codes are often used in research to identify patients with opioid use disorder (OUD), but their accuracy for this purpose is not fully evaluated. This study describes application of ICD-10 diagnosis codes for opioid use, dependence and abuse from an electronic health record (EHR) data extraction using data from the clinics' OUD patient registries and clinician/staff EHR entries.

designCross-sectional observational study.

settingFour rural primary care clinics in Washington and Idaho, USA.

participants307 patients. MEASUREMENTS: This study used three data sources from each clinic: (1) a limited dataset extracted from the EHR, (2) a clinic-based registry of patients with OUD and (3) the clinician/staff interface of the EHR (e.g. progress notes, problem list). Data source one included records with six commonly applied ICD-10 codes for opioid use, dependence and abuse: F11.10 (opioid abuse, uncomplicated), F11.20 (opioid dependence, uncomplicated), F11.21 (opioid dependence, in remission), F11.23 (opioid dependence with withdrawal), F11.90 (opioid use, unspecified, uncomplicated) and F11.99 (opioid use, unspecified with unspecified opioid-induced disorder). Care coordinators used data sources two and three to categorize each patient identified in data source one: (1) confirmed OUD diagnosis, (2) may have OUD but no confirmed OUD diagnosis, (3) chronic pain with no evidence of OUD and (4) no evidence for OUD or chronic pain.

findingsF11.10, F11.21 and F11.99 were applied most frequently to patients who had clinical diagnoses of OUD (64%, 89% and 79%, respectively). F11.20, F11.23 and F11.90 were applied to patients who had a diagnostic mix of OUD and chronic pain without OUD. The four clinics applied codes inconsistently.

conclusionsLack of uniform application of ICD diagnosis codes make it challenging to use diagnosis code data from EHR to identify a research population of persons with opioid use disorder.

Indexed as

Chronic PainOpioid-Related DisordersAnalgesics, OpioidCross-Sectional StudiesHumansInternational Classification of DiseasesAnalgesics, OpioidICD codesInternational Classification of Diseasesopioid abuseopioid dependenceopioid useopioid use disorderOUDprimary carerural

Identifiers

PMID37715369
PMCPMC10846664
OpenAlexW4386796231

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.