Evidence map›Paper›PMID 37715299›Full record

ArticlePathogens and disease2023

Bald sea urchin disease shifts the surface microbiome on purple sea urchins in an aquarium.

Chloe G Shaw, Christina Pavloudi, Megan A Barela Hudgell, Ryley S Crow, Jimmy H Saw, R Alexander Pyron, L Courtney Smith

Abstract read
In one paragraph

Article in Pathogens and disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chloe G ShawDepartment of Biological Sciences, Suite 6000 Science and Engineering Hall, 800 22nd St NW, Washington DC 20052, United States.
Christina PavloudiDepartment of Biological Sciences, Suite 6000 Science and Engineering Hall, 800 22nd St NW, Washington DC 20052, United States.
Megan A Barela HudgellDepartment of Biological Sciences, Suite 6000 Science and Engineering Hall, 800 22nd St NW, Washington DC 20052, United States.
Ryley S CrowDepartment of Biological Sciences, Suite 6000 Science and Engineering Hall, 800 22nd St NW, Washington DC 20052, United States.
Jimmy H SawDepartment of Biological Sciences, Suite 6000 Science and Engineering Hall, 800 22nd St NW, Washington DC 20052, United States.ORCID 0000-0001-8353-3854
R Alexander PyronDepartment of Biological Sciences, Suite 6000 Science and Engineering Hall, 800 22nd St NW, Washington DC 20052, United States.
L Courtney SmithDepartment of Biological Sciences, Suite 6000 Science and Engineering Hall, 800 22nd St NW, Washington DC 20052, United States.ORCID 0000-0001-7099-7852

Funding

George Washington UniversityNational Science Foundation IOS 1855747
6 · The paper itself

Abstract

Bald sea urchin disease (BSUD) is most likely a bacterial infection that occurs in a wide range of sea urchin species and causes the loss of surface appendages. The disease has a variety of additional symptoms, which may be the result of the many bacteria that are associated with BSUD. Previous studies have investigated causative agents of BSUD, however, there are few reports on the surface microbiome associated with the infection. Here, we report changes to the surface microbiome on purple sea urchins in a closed marine aquarium that contracted and then recovered from BSUD in addition to the microbiome of healthy sea urchins in a separate aquarium. 16S rRNA gene sequencing shows that microhabitats of different aquaria are characterized by different microbial compositions, and that diseased, recovered, and healthy sea urchins have distinct microbial compositions, which indicates that there is a correlation between microbial shifts and recovery from disease.

Indexed as

Sea UrchinsSeawaterAnimalsBacteriaGenomeMicrobiotaPenicillinsPolymerase Chain ReactionRNA, BacterialRNA, Ribosomal, 16SStreptomycinPenicillinsRNA, BacterialRNA, Ribosomal, 16SStreptomycin16S rRNA high throughput sequencingbacterial infectionechinodermmicrobiomeStrongylocentrotus purpuratus

Identifiers

PMID37715299
PMCPMC10550250

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.