Evidence map›Paper›PMID 37715284›Full record

ArticleBMC rheumatology2023

Cardiac sarcoma presenting as paraneoplastic arthritis and clubbing: a case report and literature review.

Natasha Ung, Carmella Gunasingam, Ken Cai, Nicholas Manolios, Angela Bayly, Phuong Dinh, Yishay Orr, Preeti Choudhary, Peter Wong

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC rheumatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Cardiac Angiosarcoma: A Diagnostic and Therapeutic Challenge.The Kaohsiung journal of medical sciences · 2025
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Natasha UngDepartment of Rheumatology, Westmead Hospital, Cnr Hawkesbury Road and Darcy Road, Westmead, NSW, 2145, Australia.
Carmella GunasingamDepartment of Rheumatology, Westmead Hospital, Cnr Hawkesbury Road and Darcy Road, Westmead, NSW, 2145, Australia.
Ken CaiDepartment of Rheumatology, Westmead Hospital, Cnr Hawkesbury Road and Darcy Road, Westmead, NSW, 2145, Australia.
Nicholas ManoliosDepartment of Rheumatology, Westmead Hospital, Cnr Hawkesbury Road and Darcy Road, Westmead, NSW, 2145, Australia.
Angela BaylyDepartment of Tissue Pathology and Diagnostic Oncology, Westmead Hospital, Westmead, NSW, Australia.
Phuong DinhDepartment of Medical Oncology, Westmead Hospital, Westmead, NSW, Australia.
Yishay OrrWestmead Clinical School, Faculty of Medicine and Health Sciences, University of Sydney, Sydney, NSW, Australia.
Preeti ChoudharyWestmead Clinical School, Faculty of Medicine and Health Sciences, University of Sydney, Sydney, NSW, Australia.
Peter WongDepartment of Rheumatology, Westmead Hospital, Cnr Hawkesbury Road and Darcy Road, Westmead, NSW, 2145, Australia. Peter.Wong2@health.nsw.gov.au.ORCID http://orcid.org/0000-0002-2182-1815
The University of Sydney · AUWestmead Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiac tumours are rare, and clinical manifestations depend on the anatomical location. Symptoms can be the result of cardiac outflow anomalies, constitutional features such as fever, loss of weight, and/or paraneoplastic manifestations such as arthritis. To date, there has only been one other case report in the literature of cardiac sarcoma presenting as paraneoplastic arthropathy. CASE PRESENTATION: A 52-year-old woman presented with acute onset corticosteroid-resistant inflammatory polyarthralgia, clubbing and a systolic murmur. Transthoracic echocardiogram revealed a dilated left atrium with an echogenic mass and brain magnetic resonance imaging revealed multiple embolic infarcts. Histopathology following emergency resection showed a Grade 3 left atrial intimal sarcoma. The polyarthralgia and clubbing resolved soon after tumour removal. The patient went on to receive chemotherapy and remains in remission.

conclusionsThis case highlights the rare paraneoplastic association of cardiac sarcoma and arthropathy.

Indexed as

ArthritisCardiac sarcomaParaneoplastic syndrome

Identifiers

PMID37715284
PMCPMC10503070
OpenAlexW4386776736

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.